Results 61 to 70 of about 35,678 (209)

Les médicaments dans les hôpitaux de la Marche au XVIIIe siècle

open access: yesHistoire, Médecine et Santé, 2012
Hospitals located in the rural province of Marche in the eighteenth century were houses bequeathed by individuals, where the “sick poor” were welcomed, fed and medicated.
Cédric Gourjault
doaj   +1 more source

Metabolomic Mapping of Greek Olive Leaves by Untargeted NMR‐Based Profiling and LC–HRMS Dereplication

open access: yesAnalytical Science Advances, Volume 7, Issue 2, December 2026.
ABSTRACT Olive tree leaves are phytochemically rich yet insufficiently valorised in terms of systematic cultivar‐based characterisation and exploitation, and are an abundant olive industry side‐product. This study represents the first large‐scale metabolome mapping based on 340 leaf extracts from five major Greek cultivars (Amfissis, Koroneiki, Manaki,
Mariacaterina Lianza   +5 more
wiley   +1 more source

Comparative Pharmacokinetics of Six Bioactive Constituents From Danggui Jixueteng Decoction in Normal and Myelosuppressive Rats

open access: yesAnalytical Science Advances, Volume 7, Issue 2, December 2026.
ABSTRACT This study compared the pharmacokinetics of six constituents from Danggui Jixueteng Decoction in normal versus carboplatin‐induced myelosuppressive rats. A rapid, sensitive ultra‐high performance liquid chromatography‐tandem mass spectrometry method was developed and validated for simultaneous quantification of six diverse constituents (8‐O ...
Mingxin Guo   +3 more
wiley   +1 more source

Design‐Assisted Chemometric UV Spectrophotometric Determination of Candesartan Cilexetil, Chlorthalidone and Amlodipine Using Principal Component Regression, Partial Least Squares and Genetic Algorithm‐Partial Least Squares Models

open access: yesAnalytical Science Advances, Volume 7, Issue 2, December 2026.
ABSTRACT This study presents a sustainable chemometric‐assisted UV spectrophotometric strategy for the simultaneous determination of candesartan cilexetil (CAN), chlorthalidone (CTL) and amlodipine (AML) in laboratory‐prepared mixtures and commercial pharmaceutical formulations.
Khanda F. M. Amin   +3 more
wiley   +1 more source

History and current status of biological tests in Russia

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2018
«Pyrogenicity» and «Abnormal Toxicity» are considered to be among most problematic pharmacopoeia monographs in the current editions of the leading world pharmacopoeias, the reasonability of which is not obvious to all experts.
M. S. Ryabtseva   +5 more
doaj  

Pharmacopoeia: Illness narratives [PDF]

open access: yesBritish Journal of Clinical Pharmacology, 2021
Liz Lee, Susie Freeman
openaire   +2 more sources

GMP‐compliant production, validation and dosimetry of clinical grade [18F]3‐(3‐fluoropropyl)‐2‐phenyl‐2,3‐dihydrobenzo[d]thiazole ([18F]FPBT) for oxidative stress PET imaging

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 20, Page 6028-6045, October 2026.
Background and Purpose Oxidative stress plays a critical role in the pathophysiology of various diseases, yet current methods for its non‐invasive detection remain limited. This study aimed to systematically validate a superoxide‐selective PET tracer, [18F]FPBT, for the early diagnosis and therapeutic monitoring of oxidative stress‐related conditions ...
Hua Zhang   +10 more
wiley   +1 more source

Metal Ions in Longgu (Fossilized Bone) as a Natural Synergistic Network for Multi‐Target Therapy in Psychiatric Disorders

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Longgu (fossilized bone) delivers a natural synergistic network of metal ions, Ca2+, Mg2+, Zn2+, Fe, Cu, and Mn2+ that collectively targets the interconnected pathologies of anxiety, depression, and insomnia. This multi‐ion system operates through coordinated mechanisms including ionostatic balance, cross‐pathway synergy, and systemic integration ...
Sun Xiujia   +7 more
wiley   +1 more source

Phytochemical Characterization of Extracts From Aesculus hippocastanum L. Seeds and Quantification of Saponins Using HPLC‐DAD and a Novel Tensiometric Approach

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Aesculus hippocastanum L. seed extracts prepared according to pharmacopeial methods were comprehensively characterized using HPLC‐DAD‐ESI‐MSn and GC‐MS. Furthermore, a novel bubble pressure tensiometric approach and an HPLC‐DAD method were employed for the quantitative analysis of surface‐active components.
Khadijeh Nosrati Gazafroudi   +6 more
wiley   +1 more source

Terminological and Grammatical Study of Essential and Fatty Oils of Plants from the Austrian, Hungarian, Spanish, and Belgian Pharmacopoeias (19th Century)

open access: yesScientia Pharmaceutica
In this study, a terminological and grammatical survey of essential and fatty oils of plant origin was performed in the selected Austrian, Hungarian, Spanish, and Belgian pharmacopoeias from the 18th to 19th centuries.
Zsuzsanna Takáts   +4 more
doaj   +1 more source

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