Small-scale dissolution test screening tool to select potentially substandard and falsified (SF) medicines requiring full pharmacopoeial analysis [PDF]
Scientific Reports, 2021 AbstractThe purpose of this study was to design a convenient, small-scale dissolution test for extracting potential substandard and falsified (SF) medicines that require full pharmacopoeial analysis. The probability of metronidazole samples complying with the US Pharmacopoeia (USP) dissolution test for immediate-release tablet formulations was ...
Mohammad Sofiqur Rahman +5 more
openaire +3 more sources
Analytical Quality by Design-Guided Optimisation and Validation of a Short-Run Stability-Indicating Reverse-Phase Ultra-Fast Liquid Chromatography (RP-UFLC) Method for the Quantitation of Nonivamide. [PDF]
Biomed ChromatogrABSTRACT Nonivamide (NON), a capsaicin analogue with similar pharmacological effects, is used in pain management, yet limited information exists on its accurate quantification by reverse‐phase liquid chromatography. A cost‐effective, efficient and precise RP‐HPLC method was developed, optimised using response surface methodology (central composite ...
Mahlangu P +3 more
europepmc +2 more sources
Comparative Analysis of Quality Requirements for Medicines Based on Horse-Chestnut Seeds
Регуляторные исследования и экспертиза лекарственных средств, 2023 Scientific relevance. When harmonising conditions for qualitative and quantitative analysis of bioactive compounds in herbal medicines, the Institute of Pharmacopoeia and Medicinal Product Standardisation has discovered that horse-chestnut products lack ...
O. V. Evdokimova +3 more
doaj +1 more source
Регуляторные исследования и экспертиза лекарственных средств, 2023 Scientific relevance. Zinc quantification in insulin active substances and preparations by atomic absorption spectrometry requires a sample preparation procedure using hydrochloric acid, a narcotic and psychotropic precursor.
A. A. Erina +3 more
doaj +1 more source
Quality of fixed dose artemether/lumefantrine products in Jimma Zone, Ethiopia [PDF]
, 2019 Background: Malaria caused by Plasmodium vivax and Plasmodium falciparum is among the major public health problems in most endemic areas of the world.
Bayisa, Bikila +10 more
core +1 more source
A rapid stability-indicating, fused-core HPLC method for simultaneous determination of β-artemether and lumefantrine in anti-malarial fixed dose combination products [PDF]
, 2013 Background: Artemisinin-based fixed dose combination (FDC) products are recommended by World Health Organization (WHO) as a first-line treatment. However, the current artemisinin FDC products, such as beta-artemether and lumefantrine, are inherently ...
Bracke, Nathalie +8 more
core +2 more sources
Nanotechnology versus other techniques in improving drug dissolution [PDF]
, 2014 postprin
Chan, HK, Kwok, PCL
core +1 more source
Outdoor ventilation and ground coverage: Exploring a climate centric approach to building byelaws for multi storied apartments in Bhubaneswar [PDF]
, 2020 Bhubaneswar with a warm and humid climate and with humidity much higher than the comfort level requires an enhanced natural ventilation to achieve long term quality of life.
Manjari Chakraborty, Monalipa Dash
core +1 more source
Analytical Method by Headspace-Gas Chromatography for Determination of Six Residual Solvents in Losartan Potassium Raw Material. [PDF]
J Sep SciABSTRACT Residual solvents, or organic volatile impurities, are a potential toxic risk for pharmaceutical products and have been a manufacturers’ concern for many years. Moreover, residual solvents can also affect the quality and stability of not only drug substances but also of drug products.
de Camargo VB, Garcia CV.
europepmc +2 more sources
Phylogenomic approaches to DNA barcoding of herbal medicines: developing clade-specific diagnostic characters for Berberis [PDF]
, 2019 DNA barcoding of herbal medicines has been mainly concerned with authentication of products in trade and has raised awareness of species substitution and adulteration.
Acosta +65 more
core +3 more sources