Results 31 to 40 of about 52,530,193 (113)

Transcriptome Inference and Systematic Approaches to Investigate TCM Compounds With Beneficial Metabolic Effects

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Obesity is a major risk factor for type 2 diabetes. Some traditional Chinese medicine (TCM) compounds can improve obesity by increasing energy consumption. This study aimed to identify and verify TCM compounds that promote adipose thermogenesis to alleviate obesity via transcriptomic analysis, molecular docking, network pharmacology, and ...
Jing Li   +6 more
wiley   +1 more source

Immunomodulatory Properties of Withania somnifera: Regulation of Innate Immune Cells and Clinical Implications

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Withania somnifera (L.) Dunal (WS), commonly known as Ashwagandha, is a prominent medicinal herb in Ayurveda, with extensive therapeutic potential attributed to its diverse phytochemical profile. This review critically examines the immunomodulatory properties of WS, focusing on innate immune cell populations, including neutrophils, eosinophils,
Rana Yukta   +9 more
wiley   +1 more source

Ruta graveolens L. in Evidence‐Based Phytotherapy: Pharmacological Activities, Bioactive Compounds and Safety

open access: yesPhytotherapy Research, EarlyView.
Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko   +3 more
wiley   +1 more source

Pre‐Seasonal Treatment With Recombinant Carrier‐Based Birch Vaccine Improves Birch Pollen Allergy

open access: yesAllergy, EarlyView.
We conducted a two stage SCIT trial with GNR‐127 containing a recombinant fusion protein consisting of Bet v 1 and Mal d 1‐derived peptides fused to PreS from HBV. Stage 1 identified two safe maximum tolerated doses (40 μg and 80 μg). In the following Stage 2, five preseasonal injections were well tolerated, induced dose‐dependent allergen‐specific IgG,
Musa R. Khaitov   +43 more
wiley   +1 more source

A prospective randomised comparison of two different stenting sutures when using the Baerveldt 101–350 aqueous shunt – Lab transition to clinical process

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose The Baerveldt glaucoma drainage implant (BGI 101–350) is one of the most effective treatment options for managing refractory glaucoma. To mitigate early hypotony in non‐valved implants, intraluminal occluding sutures (IOSs) are commonly used.
Evripidis Sykakis   +7 more
wiley   +1 more source

Concept Extraction and Clustering for Topic Digital Library Construction [PDF]

open access: yes, 2008
This paper is to introduce a new approach to build topic digital library using concept extraction and document clustering. Firstly, documents in a special domain are automatically produced by document classification approach.
Dan, Wu, Chengzhi, Zhang
core   +1 more source

Apropos the topic On topic-introducing expressions in Swedish

open access: yes, 2019
The inquiry into topicality calls for a deeper understanding of explicit "topic markers" such as apropos and concerning, which are found in many if not all the languages of Europe.
Egerland, Verner,, Lund University.
core   +1 more source

Unravelling polyphenol skin permeation: A comparative study using full‐thickness 3D in vitro and ex vivo human skin models

open access: yesInternational Journal of Cosmetic Science, EarlyView.
This study demonstrates that full‐thickness 3D in vitro skin models reliably assess the permeation of cosmetic polyphenols, revealing compound‐specific transport profiles and bridging the gap between conventional cell models and ex vivo human skin, while offering an ethical and robust alternative for dermal absorption screening. Abstract The evaluation
Mariana Marques   +6 more
wiley   +1 more source

Synergistic enhancement SPF from annatto seed oil and alkaline extracts in association with organic UV filters

open access: yesInternational Journal of Cosmetic Science, EarlyView.
An SPF formulation incorporating Bixa orellana seed extracts and oils showed enhanced UV protection, highlighting the potential of natural bioactive compounds as effective boosters in photoprotective cosmetic products. Abstract Objective This study investigated the antioxidant activity of oil and alkaline aqueous extracts obtained from Bixa orellana ...
Ister Cordeiro Mariotini   +8 more
wiley   +1 more source

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