Results 91 to 100 of about 301,634 (281)

Effects of Antiepileptic Drugs, Carbamazepine and Phenytoin, on Plasma Concentrations of Clozapine and Its N‐Desmethyl and N‐Oxide Metabolites in Japanese Patients With Schizophrenia

Neuropsychopharmacology Reports
Clozapine (CLZ) is used for treatment‐resistant schizophrenia. However, in Japanese patients, its pharmacokinetics are still not well described, and there are no case reports about drug interactions between CLZ and concomitant antiepileptics that can ...
Kazuro Ikawa, Tomoya Imura, Saori Nakamura, Kanae Murata, Norifumi Morikawa, Mutsumi Sakata, Hidenori Yasuzawa, Naoki Horikawa   +7 more
doaj   +1 more source

Role of pharmacotherapy in Brugada syndrome [PDF]

, 2004
In patients who undergo aborted sudden cardiac death or syncope of unknown origin (symptomatic Brugada syndrome), no one argues that the implantation of an ICD is the first-line therapy regardless of the findings of the EP study.
Tsuchiya, Takeshi
core   +1 more source

Can We Really Prevent Suicide? [PDF]

, 2012
Every year, suicide is among the top 20 leading causes of death globally for all ages. Unfortunately, suicide is difficult to prevent, in large part because the prevalence of risk factors is high among the general population. In this review, clinical and
A Fagiolini, A Roy, A Roy, AC Leon, AD Lopez, AF Jorm, AL Beautrais, AN Sabo, AP Chioqueta, B Schneider, B Schneider, B Spivac, B Stanely, B Stanley, B Yerevanian, BA Palmer, BN Gaynes, C Bushe, C Haw, CM Feltz-Cornelis van der, CW Tsai, D Fergusson, D Gunnell, D Shaffer, D Wasserman, DA Brent, DA Brent, DA Brent, EC Harris, F Cassidy, F Guzzetta, F Keller, FK Goodwin, FS Bridges, G Dieserud, G Isacsson, G Isacsson, G Sonneck, Gil Zalsman, GK Brown, GL Carter, GL Sidley, H Dumesnil, H Galfalvy, H Valtonen, HG Morgan, HJ Moller, HJ Moller, HJ Moller, HY Meltzer, J Fawcet, J Johnson, J Lonnqvist, JA Egeland, JB Luoma, JD Maser, JJ Lin, JJ Mann, JJ Mann, JM Boden, JMG Williams, K Hawton, K Hor, K Posner, K Szanto, KL Knox, KM Malone, L Tondo, LM Hayes, Lucas Giner, M Bauer, M Bauer, M Leitner, M Miller, M Olfson, M Panagioti, M Pompili, M Sarchiapone, M Shelef, MA Oquendo, MA Oquendo, MA Oquendo, MA Oquendo, Maria A. Oquendo, Maya Schwartz-Lifshitz, MD Rudd, MM Linehan, MP Pignone, N Tarrier, ND Kapusta, NM Melhem, O Bennewith, PA Wyman, PG Placidi, PH Soloff, PH Soloff, RD Gibbons, RJ Baldessarini, S Kelly, SH Kennedy, SP Pirkola, U Hegerl, U Hegerl, U Hegerl, UA Andersen, W Coryell, WA Watson, WD Hall, Z Rihmer, Z Rihmer, Z Rihmer, Z Rihmer   +111 more
core   +1 more source

From cramming to binge‐watching: Integrating documentary‐based assessment into a pharmacology and toxicology curriculum—a qualitative study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims In the context of pharmacology and toxicology education, there is a growing shift toward programmatic assessment models that prioritize longitudinal learning, reflection and development of higher‐order cognitive skills. As part of this transition, we are exploring alternative and more meaningful forms of assessment. This qualitative study
Narin Akrawi, Heleen van der Sijs, Floor van Rosse   +2 more
wiley   +1 more source

Cluster headache: a quasi-rare disorder needing a reappraisal [PDF]

, 2015
Editoria
Martelletti, Paolo, Mitsikostas, Dimos Dimitrios   +1 more
core   +1 more source

Evaluating and leveraging large language models in clinical pharmacology and therapeutics assessment: From exam takers to exam shapers

British Journal of Clinical Pharmacology, EarlyView.
Aims In medical education, the ability of large language models (LLMs) to match human performance raises questions about their potential as educational tools. This study evaluates LLMs' performance on Clinical Pharmacology and Therapeutics (CPT) exams, comparing their results to medical students and exploring their ability to identify poorly formulated
Alexandre O. Gérard, Diane Merino, Marc Labriffe, Fanny Rocher, Delphine Viard, Laurence Zemori, Thibaud Lavrut, Erik M. Donker, Joost D. Piët, Jean‐Paul Fournier, Milou‐Daniel Drici, Alexandre Destere   +11 more
wiley   +1 more source

Impact of antiviral prophylaxis on EBV viremia and posttransplant lymphoproliferative disorders in solid organ transplant recipients: a systematic review and meta-analysis

Virology Journal
Introduction Organ transplant recipients face a substantial risk of developing posttransplant lymphoproliferative disorders (PTLD). In over 90% of cases with B‐cell PTLD following solid organ transplantation, the Epstein‐Barr virus (EBV) genome is ...
Marjan Moghadamnia, Khadijeh Delroba, Shima Heidari, Zahra Rezaie, Simin Dashti-Khavidaki   +4 more
doaj   +1 more source

The integration of the British Pharmacological Society's prescription safety assessment into the WHO 6‐step model of rational pharmacotherapy in a Turkish medical school

British Journal of Clinical Pharmacology, EarlyView.
Aims At Koç University School of Medicine, a one‐week rational pharmacotherapy (RPHM) programme, modelled after WHO 6‐step, has been introduced in the fourth‐year curriculum to improve prescription skills. For efficient problem‐based learning (PBL) sessions on a prespecified topic, students need to brush up on basic pharmacology knowledge, so we ...
Sinem Ezgi Gülmez, Gülnihal Özcan, Hakan S. Orer   +2 more
wiley   +1 more source

Prescription procedures in medication for relapse prevention after inpatient treatment for alcohol use disorders in Switzerland [PDF]

, 2017
Aims: In randomized controlled trials with high internal validity, pharmacotherapy using acamprosate, naltrexone, and, to a somewhat lesser extent, disulfiram has proved effective in preventing relapse in patients with alcohol use disorders (AUD).
Buri, Caroline, Giovanoli, Anna, Moggi, Franz, Strik, Werner   +3 more
core  

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source