Results 171 to 180 of about 131,053 (266)

Effects of catechins, resveratrol, silymarin components and some of their conjugates on xanthine oxidase‐catalyzed xanthine and 6‐mercaptopurine oxidation

Journal of the Science of Food and Agriculture, Volume 105, Issue 5, Page 2765-2776, 30 March 2025.
Abstract BACKGROUND Over the past two decades, the global incidence of gout has markedly increased, affecting people worldwide. Considering the side effects of xanthine oxidase (XO) inhibitor drugs (e.g. allopurinol and febuxostat) used in the treatment of hyperuricemia and gout, the potential application of phytochemicals has been widely studied.
Tímea Bencsik, Orsolya Balázs, Róbert G Vida, Balázs Z Zsidó, Csaba Hetényi, Kateřina Valentová, Miklós Poór   +6 more
wiley   +1 more source

Correction: Pharmacotherapy of major depressive disorder in older adults: from an evidence-informed stepwise algorithm to precision medicine. [PDF]

Neuropsychopharmacology
Lenze EJ, Karp JF, Gebara MA, Nicol GE, Mulsant BH.   +4 more
europepmc   +1 more source

Prehabilitation Prior to Colorectal Cancer Surgery: Impact and Implementation

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives Multimodal prehabilitation aims to improve surgical outcomes and preoperative fitness in patients undergoing surgery for colorectal cancer (CRC). This study evaluated implementation of a standardised prehabilitation programme for elective CRC surgery, assess its impact, and identify pitfalls and challenges during ...
Elize W. Lockhorst, Theresia A. M. Backhuijs, Teun M. E. Kerkhoff, Robert R. J. Coebergh van den Braak, Ninos Ayez, Cornelis Verhoef, Paul D. Gobardhan, Jennifer M. J. Schreinemakers   +7 more
wiley   +1 more source

Translating Evidence into Obstetric Care: Developing a Best Practice-Informed Stepped-Care Clinical Algorithm for the Management of Gestational Insomnia. [PDF]

Nat Sci Sleep
Zhao FY, Yue LP, Ho YS, Xu P, Broadbear JH, Zhang WJ, Wang YM, Fu QQ, Conduit R.   +8 more
europepmc   +1 more source

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

Examining the Impact of Trial Length on Detecting Medication Effects for Alcohol Use Disorder: A Meta-Regression Study. [PDF]

Alcohol Clin Exp Res (Hoboken)
Belnap MA, Witkiewitz K, Schacht JP, Anton RF, Aldridge AP, Nieto SJ, Ray LA.   +6 more
europepmc   +1 more source

Managing the meniscus part I—Anatomy, biomechanics, and treatment strategies for the atraumatic meniscus tear

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The purpose of this article is to serve as the first of a two‐part review on the meniscus; in this review, we will establish the background on anatomy and pathogenesis of the meniscus, as well as the effect of the meniscus on native knee kinematics and function.
Ehab M. Nazzal, Jonathan D. Hughes, Armin Runer, Matthew P. Kolevar, Jorge Chahla, Robert G. Marx, James J. Irrgang, Roman Seil, Berte Bøe, David Parker, Ryosuke Kuroda, Eric H. Senorski, Sachin Tapasvi, Volker Musahl   +13 more
wiley   +1 more source

Integrated behavioral care in general hepatology increases alcohol use disorder treatment in veterans. [PDF]

Hepatol Commun
Perumalswami PV, Cornwell BL, Grau PP, Meyers AC, Jayaram M, Irani S, Wongsirisakul P, Liangpunsakul S, Patel A, DePhilippis D, Liberto J, Szymanski BR, McCarthy JF.   +12 more
europepmc   +1 more source

Ménière's Disease: A Tri‐Decade Scoping Review of Treatment Trends and Evidence Quality

The Laryngoscope, EarlyView.
This tri‐decade scoping review of Ménière's disease literature reveals a significant increase in high‐level evidence and a clinical pivot toward hearing‐preserving interventions, such as intratympanic steroids and cochlear implants. However, a significant quality paradox has emerged, where adherence to standardized AAO‐HNS reporting and diagnostic ...
Ofir Zavdy, Teeraya Piyajarawong, Seamus Boyle, Ross O'Shea, John Rutka   +4 more
wiley   +1 more source

Global research landscape in pharmacotherapy for autism spectrum disorder core symptoms: a bibliometric study. [PDF]

Transl Pediatr
Cai C, Bao S, Ran Q, Lu M, Song C, Jiang Z.   +5 more
europepmc   +1 more source