Results 1 to 10 of about 47,791 (152)
British Journal of Haematology, 2019 Eculizumab is the first and only medication approved for paroxysmal nocturnal haemoglobinuria (PNH) and atypical haemolytic uraemic syndrome (aHUS) treatment. However, eculizumab safety based on long‐term pharmacovigilance is unknown.
Gérard Soci +2 more
exaly +2 more sources
PHEE: A Dataset for Pharmacovigilance Event Extraction from Text [PDF]
Conference on Empirical Methods in Natural Language Processing, 2022 The primary goal of drug safety researchers and regulators is to promptly identify adverse drug reactions. Doing so may in turn prevent or reduce the harm to patients and ultimately improve public health.
ZHAOYUE SUN +7 more
semanticscholar +1 more source
Considerations on the use of different comparators in pharmacovigilance: A methodological review
British Journal of Clinical Pharmacology, 2023 Pharmacovigilance studies based on spontaneous reporting systems use disproportionality analysis methods to identify drug‐event combinations with higher‐than‐expected reporting. Enhanced reporting is deemed as a proxy for a detected signal and is used to
Christopher A Gravel, A. Douros
semanticscholar +1 more source
Scientific Reports, 2022 Increasing number of Janus kinase (JAK) inhibitors have been approved for chronic haematopoietic neoplasms and inflammatory/autoimmune diseases.
L. Hoisnard +13 more
semanticscholar +1 more source
PLoS ONE, 2023 Background Healthcare professionals’ involvement and reporting of adverse drug reactions are essential for the success of a pharmacovigilance program.
Z. Khan +2 more
semanticscholar +1 more source
Pharmacovigilance in High-Income Countries: Current Developments and a Review of Literature
Pharmacy, 2023 The world bank has classified 80 economies based on their Gross National Income (GNI) per capita as High-Income. European Medicines Agency (EMA), Food and Drug Administration (FDA), and Pharmaceuticals and Medical Devices Agency (PMDA) are the major ...
Muhammad Akhtar Abbas Khan +2 more
semanticscholar +1 more source
Nature Communications, 2022 While multiple pharmacological drugs have been associated with myocarditis, temporal trends and overall mortality have not been reported. Here we report the spectrum and main features of 5108 reports of drug-induced myocarditis, in a worldwide ...
L. Nguyen +16 more
semanticscholar +1 more source
JAMA Internal Medicine, 2021 Association of Facial Paralysis With mRNA COVID-19 Vaccines: A Disproportionality Analysis Using the World Health Organization Pharmacovigilance Database During the pivotal phase 3 clinical trials of mRNA COVID-19 vaccines, several cases of facial ...
Lucie Renoud +6 more
semanticscholar +1 more source
“Artificial Intelligence” for Pharmacovigilance: Ready for Prime Time?
Drug Safety, 2022 There is great interest in the application of ‘artificial intelligence’ (AI) to pharmacovigilance (PV). Although US FDA is broadly exploring the use of AI for PV, we focus on the application of AI to the processing and evaluation of Individual Case ...
R. Ball, G. D. Dal Pan
semanticscholar +1 more source
Artificial Intelligence Based on Machine Learning in Pharmacovigilance: A Scoping Review
Drug Safety, 2022 Introduction Artificial intelligence based on machine learning has made large advancements in many fields of science and medicine but its impact on pharmacovigilance is yet unclear.
Benjamin Kompa +9 more
semanticscholar +1 more source