Results 11 to 20 of about 48,983 (212)

Safety of sulfamethoxazole-trimethoprim for the treatment of bacterial infection in outpatient settings: A systematic review and meta-analysis with active comparator disproportionality analysis. [PDF]

Br J Clin Pharmacol
Aims Sulfamethoxazole–trimethoprim (SMX‐TMP) is a widely used antibiotic for treating bacterial infections, but its safety in adult outpatients remains understudied. This systematic review and meta‐analysis evaluated the safety profile of SMX‐TMP and identified critical research gaps.
Preyra R, Eddin LE, Ahmadi F, Jafari A, Muanda FT.   +4 more
europepmc   +3 more sources

Pharmacovigilance of Biosimilars [PDF]

, 2013
In lieu of an abstract, here is the article\u27s first paragraph: Biotech industry forms the backbone of the current pharmaceutical products. Seven out of top ten anticipated drugs of the industry in 2014 will be biologics [1].
Chablani, Lipika
core   +2 more sources

How pharmacoepidemiology networks can manage distributed analyses to improve replicability and transparency and minimize bias [PDF]

, 2020
Several pharmacoepidemiology networks have been developed over the past decade that use a distributed approach, implementing the same analysis at multiple data sites, to preserve privacy and minimize data sharing.
Brown, Jeffrey S., Henry, David A., Klungel, Olaf H., Platt, Richard, Platt, Robert W., Suissa, Samy   +5 more
core   +2 more sources

Bayesian model selection in logistic regression for the detection of adverse drug reactions [PDF]

, 2015
Motivation: Spontaneous adverse event reports have a high potential for detecting adverse drug reactions. However, due to their dimension, exploring such databases requires statistical methods.
Marbac, Matthieu, Sedki, Mohammed, Tubert-Bitter, Pascale   +2 more
core   +2 more sources

Linked health data for pharmacovigilance in children : Perceived legal and ethical issues for stakeholders and data guardians [PDF]

, 2014
Peer reviewedPublisher ...
Bond, Christine M, Francis, Jill J, Haughney, John, Helms, Peter J, Hopf, Yvonne Marina   +4 more
core   +2 more sources

Pharmacists in Pharmacovigilance: Can Increased Diagnostic Opportunity in Community Settings Translate to Better Vigilance? [PDF]

, 2014
The pharmacy profession has undergone substantial change over the last two to three decades. Whilst medicine supply still remains a central function, pharmacist’s roles and responsibilities have become more clinic and patient focused.
AG Granas, AI Wertheimer, B Gray, C Gonzalez-Gonzalez, C Su, Christine Randall, Consumers’ Association, Consumers’ Association, Consumers’ Association, D Brown, D Stewart, David Brown, DM Ashcroft, E Horsley, E Kroger, E Richardson, G Marchildon, GD Lansam, JK Jesson, Justine Howard, K Grootheest van, KB Blake, L Emmerton, L Hanna, M Jadeja, M Rosenthal, M Tobaiqy, MA Hadi, MP Smith, N Black, N Iqbal, P Chan, P Gavaza, P Rutter, Paul Rutter, S Keyhani, SS Sardas, T Kimura, V Paudyal, Z Austin   +39 more
core   +1 more source

Adverse Effects of Cholinesterase Inhibitors in Dementia, According to the Pharmacovigilance Databases of the United-States and Canada. [PDF]

, 2015
This survey analyzes two national pharmacovigilance databases in order to determine the major adverse reactions observed with the use of cholinesterase inhibitors in dementia.
Abagyan, Ruben, Ali, Thibault B, Chen, Winston Yuchen, Reilly, Brian M, Schleret, Thomas R   +4 more
core   +3 more sources

Antipsychotics and Torsadogenic Risk: Signals Emerging from the US FDA Adverse Event Reporting System Database [PDF]

, 2013
Background: Drug-induced torsades de pointes (TdP) and related clinical entities represent a current regulatory and clinical burden. Objective: As part of the FP7 ARITMO (Arrhythmogenic Potential of Drugs) project, we explored the publicly available US ...
A Bate, A Clarke, A Pariente, AK Chung, Ariola Koci, B Darpo, BJ Drew, C Meyer-Massetti, DM Roden, DW Hough, E Poluzzi, E Poluzzi, E Poluzzi, E Raschi, E Raschi, Edoardo Spina, Elijah R. Behr, Elisabetta Poluzzi, Emanuel Raschi, EP Puijenbroek van, ER Behr, F Ponti De, F Ponti De, F Rani, Fabrizio De Ponti, GC Alexander, GK Isbister, H Verdoux, J Nielsen, J Papay, K Jolly, K Titier, LC Wittkampf, LS Schneider, Miriam Sturkenboom, NP Tatonetti, P Kannankeril, P Manu, P Vigneault, RC Owens Jr, RR Shah, S Dhillon, S Hennessy, S Kongsamut, S Leucht, SM Straus, Ugo Moretti, W Crumb, W Crumb, WA Ray, WA Ray, WJ Crumb Jr, WP Stephenson, Y Suzuki   +53 more
core   +3 more sources

Reported adverse drug reactions during the use of inhaled steroids in children with asthma in the Netherlands [PDF]

, 2006
Objective: Inhaled corticosteroids (ICS) are widely used in the treatment of asthma. We studied the suspected adverse drug reactions (sADRs) reported during the use of ICS in the Netherlands. Methods: In the Netherlands, health professionals and patients
de Jong-van den Berg, L.T.W., de Vries, T.W., Duiverman, E.J., Langen-Wouterse, J.J., van Puijenbroek, E.   +4 more
core   +1 more source

What Affects the Quality of Pharmacovigilance? Insights From Qualitative Comparative Analysis. [PDF]

Pharmacol Res Perspect
ABSTRACT Pharmacovigilance plays a significant role in guaranteeing the safety of medications for patients. Over the last three decades, China has significantly advanced its pharmacovigilance practices, yet the factors that drive the quality of pharmacovigilance remain unclear.
Wang Y, Chen Y, Xu X, Ying T, Xia R, Zhang Y, Xie X.   +6 more
europepmc   +2 more sources