Abstract Aim This study aims to conduct a hypothesis‐generating screening for acute cardiovascular effects of prescription medications. Methods This Danish nationwide screening study was conducted among incident cases of cardiovascular diseases, including myocardial infarction (MI), ischemic stroke (IS), heart failure (HF), venous thromboembolism (VTE),
Saad Hanif Abbasi+4 more
wiley +1 more source
A National Adverse Drug Reaction Reporting System for Malta [PDF]
The mission of the Medicines Authority (MA) in Malta is to contribute to protection of public health through regulation of the safety, quality and efficacy of medicines for human use on the local market and to ensure that healthcare professionals and ...
Arthur, Niamh+2 more
core
Abstract The development of humanized IgG1 anti‐amyloid monoclonal antibodies, such as lecanemab, provides a promising novel treatment pathway with potential disease‐modifying effects for patients with early Alzheimer's disease (AD). Lecanemab, which gained marketing approval by the United States Food and Drug Administration (US FDA) in July 2023, has ...
Amy Bobbins+5 more
wiley +1 more source
The Future of Generic Biologics: Should the United States “Follow-On” the European Pathway? [PDF]
The United States is embarking on a biotechnology drug revolution. In the last few decades, biotech drugs have saved millions of lives, and the market for these miracle cures continues to grow at an astronomical rate.
Aili, Daniel+6 more
core +4 more sources
Aromatase Inhibitors and Dementia Risk: Putting Safety Into Perspective. [PDF]
Pharmacology Research &Perspectives, Volume 13, Issue 3, June 2025.
Rizk M, Mokbel K.
europepmc +2 more sources
Aims The incidence of postmenopausal bleeding (PMB) has been increasing over the past years. Little is known about the risk of PMB after COVID‐19 vaccination. Our study aimed to investigate this based on routine general practitioner (GP) healthcare data from the Netherlands.
Rana Jajou+5 more
wiley +1 more source
Conceptual graph-based knowledge representation for supporting reasoning in African traditional medicine [PDF]
Although African patients use both conventional or modern and traditional healthcare simultaneously, it has been proven that 80% of people rely on African traditional medicine (ATM).
Diallo, Gayo+2 more
core +2 more sources
EudraVigilance insights: Suspected adverse drug reactions in infants through breastfeeding
Aims We aimed to describe suspected adverse drug reactions (ADRs) in infants resulting from medications transmitted through mothers' milk, as reported to the European ADR database, EudraVigilance. The research sought to understand the frequency, seriousness and nature of these ADRs to assess potential risks associated with maternal medication use ...
Ida M. Heerfordt+7 more
wiley +1 more source
Which Pharmacovigilance for Vaccines? [PDF]
Vaccines are not separate health products but anti-infectious medicines administered for the large part prophylactically and for which the effect is immunological and not pharmacological. They should be evaluated by the usual methods of clinical pharmacology and pharmacovigilance, taking into account certain specificities (mechanism of action ...
Hervé Le Louët+11 more
openaire +4 more sources
Safety and efficacy of colistin versus meropenem in the empirical treatment of ventilator-associated pneumonia as part of a macro-project funded by the Seventh Framework Program of the European Commission studying off-patent antibiotics. study protocol for a randomized controlled trial [PDF]
Background: Ventilator-associated pneumonia (VAP) is one of the most common and severe hospital-adquired infections, and multidrugresistant gram-negative bacilli (MDR-GNB) constitute the main etiology in many countries.
Clara Rosso, Fernández+6 more
core +1 more source