Results 51 to 60 of about 47,791 (152)

Conceptual graph-based knowledge representation for supporting reasoning in African traditional medicine [PDF]

, 2013
Although African patients use both conventional or modern and traditional healthcare simultaneously, it has been proven that 80% of people rely on African traditional medicine (ATM).
Diallo, Gayo, Foguem, Clovis, Kamsu-Foguem, Bernard   +2 more
core   +2 more sources

Incidence of Adverse Drug Reactions in COVID‐19 Patients in China: An Active Monitoring Study by Hospital Pharmacovigilance System

Clinical pharmacology and therapy, 2020
To evaluate the incidence, type, and risk factors associated with adverse drug reactions (ADRs) among patients with coronavirus disease 2019 (COVID‐19) by Hospital Pharmacovigilance System (CHPS).
Ji Sun, X. Deng, Xiaoping Chen, Juanjuan Huang, Siqiong Huang, Yanfei Li, Jinhui Feng, Ji-yang Liu, Gefei He   +8 more
semanticscholar   +1 more source

Safety and efficacy of colistin versus meropenem in the empirical treatment of ventilator-associated pneumonia as part of a macro-project funded by the Seventh Framework Program of the European Commission studying off-patent antibiotics. study protocol for a randomized controlled trial [PDF]

, 2015
Background: Ventilator-associated pneumonia (VAP) is one of the most common and severe hospital-adquired infections, and multidrugresistant gram-negative bacilli (MDR-GNB) constitute the main etiology in many countries.
Clara Rosso, Fernández, DE BLASI, Roberto Alberto, George, Dimopoulos, José Garnacho, Montero, José Miguel, Cisneros, Massimo, Antonelli, The MagicBullet study, Group   +6 more
core   +1 more source

Lessons to be Learnt from Real-World Studies on Immune-Related Adverse Events with Checkpoint Inhibitors: A Clinical Perspective from Pharmacovigilance

Targeted oncology, 2020
The advent of immune checkpoint inhibitors (ICIs) caused a paradigm shift both in drug development and clinical practice; however, by virtue of their mechanism of action, the excessively activated immune system results in a multitude of off-target ...
E. Raschi, Milo Gatti, F. Gelsomino, A. Ardizzoni, E. Poluzzi, F. De Ponti   +5 more
semanticscholar   +1 more source

Validating Intelligent Automation Systems in Pharmacovigilance: Insights from Good Manufacturing Practices

Drug Safety, 2021
Pharmacovigilance is the science of monitoring the effects of medicinal products to identify and evaluate potential adverse reactions and provide necessary and timely risk mitigation measures.
Kristof Huysentruyt, Oeystein Kjoersvik, Pawel Dobracki, Elizabeth Savage, Ellen Mishalov, M. Cherry, E. Leonard, Robert Taylor, Bhavin Patel, Danielle Abatemarco   +9 more
semanticscholar   +1 more source

Disproportionality Analysis for Pharmacovigilance Signal Detection in Small Databases or Subsets: Recommendations for Limiting False-Positive Associations

Drug Safety, 2020
Introduction Uncovering safety signals through the collection and assessment of individual case reports remains a core pharmacovigilance activity. Despite the widespread use of disproportionality analysis in signal detection, recommendations are lacking ...
O. Caster, Yasunori Aoki, Lucie M. Gattepaille, B. Grundmark   +3 more
semanticscholar   +1 more source

Comorbidities of patients in tiotropium clinical trials : comparison with observational studies of patients with chronic obstructive pulmonary disease [PDF]

, 2015
Acknowledgments The authors are fully responsible for all content and editorial decisions made, were involved at all stages of manuscript development, and have approved the final version for publication.
Celli, Bartolome, Metzdorf, Norbert, Miravitlles, Marc, Price, David, Rabe, Klaus F, Schmidt, Hendrik   +5 more
core   +1 more source

Semi-Supervised Recurrent Neural Network for Adverse Drug Reaction Mention Extraction

, 2017
Social media is an useful platform to share health-related information due to its vast reach. This makes it a good candidate for public-health monitoring tasks, specifically for pharmacovigilance.
Gupta, Shashank, Palshikar, Girish, Pawar, Sachin, Ramrakhiyani, Nitin, Varma, Vasudeva   +4 more
core   +1 more source

Immune Checkpoint Inhibitor-Related Cytokine Release Syndrome: Analysis of WHO Global Pharmacovigilance Database

Frontiers in Pharmacology, 2020
Immune checkpoint inhibitors (ICIs) have proven effective in the treatment of numerous cancers; however, they have been associated with immune-related adverse events (irAEs), among which cytokine release syndrome (CRS) has been reported in a few case ...
A. Ceschi, Roberta Noseda, K. Palin, K. Verhamme   +3 more
semanticscholar   +1 more source

Clinical trials on medicinal products in Malta following EU accession [PDF]

, 2006
Following EU Accession, Malta has to adopt EU Directives as part of its own legislation. Three such directives concern the conduct of clinical trials in European countries ­ 2001/20/EC, 2003/94/EC and 2005/28/EC.
Calleja, Neville, Ellul, Ian C.
core