Results 61 to 70 of about 48,983 (212)

A Case of Hemophagocytic Lymphohistiocytosis During Immune Checkpoint Inhibitor Treatment for Metastatic Renal Cell Carcinoma, Complicated by Pancytopenia Attributed to Cytomegalovirus Infection

open access: yesIJU Case Reports, EarlyView.
ABSTRACT Introduction Hemophagocytic lymphohistiocytosis (HLH) is characterized by macrophage and cytotoxic lymphocyte hyperactivation, fever, pancytopenia, liver dysfunction, and abnormal coagulation. However, no specific treatments have been established for HLH caused by immune checkpoint inhibitors.
Tomoko Honda   +9 more
wiley   +1 more source

Heparin pharmacovigilance in Brazil

open access: yesRevista da Associação Médica Brasileira (English Edition), 2011
To investigate the biological origin of injectable unfractioned heparin available in Brazilian market by discussing the impact of the profile of commercial products and the changes in heparin monograph on the drug safety.The Anvisa data base for the Registered Products of Pharmaceutical Companies and the Dictionary of Pharmaceutical Specialties (DEF ...
Fabiana Cristina Ribeiro de Barros   +5 more
openaire   +3 more sources

Diversity and Ecological Factors Influencing Medicinal Plant Use Among Ethnolinguistic Groups in the Philippines 21世纪菲律宾人类文化语言学族群药用植物多样性及其生态关联研究

open access: yesIntegrative Conservation, EarlyView.
Plant order‐level Sankey plot illustrating plant use of ethnolinguistic groups for key disease types based on organ systems and use. Each node represents the strength of its interaction or usage. ABSTRACT Many human populations rely on natural remedies for health and healing, with traditional medicinal plants playing a vital role in diverse ...
Krizler C. Tanalgo   +15 more
wiley   +1 more source

Proceedings of the biosimilars workshop at the International Symposium on Oncology Pharmacy Practice 2019. [PDF]

open access: yes, 2020
The International Society of Oncology Pharmacy Practitioners organized a workshop to create learning opportunities on biosimilars in pharmacy practice on 10 October 2019.
Chan, Alexandre, Ke, Yu, Tan, Chia Jie
core  

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

open access: yesSmall, EarlyView.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai   +5 more
wiley   +1 more source

Pharmacovigilance: Scope for a dermatologist

open access: yesIndian Journal of Dermatology, 2011
Pharmacovigilance is defined as the science of detection, assessment, and prevention of adverse drug reactions in humans. Under-reporting of drug reactions is the major problem and has various reasons. The WHO has initiated the program of reporting all adverse drug reactions now co-ordinated by the Uppsala Monitoring Centre in Uppsala, Sweden, with ...
Gurcharan Singh, Bhanu Prakash
openaire   +4 more sources

From clinical observations to molecular insights: Decoding immune checkpoint inhibitors‐induced prostatitis

open access: yesVIEW, EarlyView.
Immune checkpoint inhibitors (ICIs), an innovative class of cancer therapeutics, may elevate the risk of prostate inflammation (prostatitis) in a subset of male patients. Our investigation demonstrated that ICIs can induce inflammatory responses in prostate tissue; however, selectively targeting specific inflammatory pathways may potentially mitigate ...
Peng Luo   +9 more
wiley   +1 more source

Can the Heinrich ratio be used to predict harm from medication errors? [PDF]

open access: yes, 2006
The purpose of this study was to establish whether, for medication errors, there exists a fixed Heinrich ratio between the number of incidents which did not result in harm, the number that caused minor harm, and the number that caused serious harm.
Barber, N   +3 more
core  

Effectiveness and Safety of Guselkumab in Patients With Moderate‐to‐Severe Plaque Psoriasis in Real‐World Practice in Korea: A Prospective, Multicenter, Observational, Postmarketing Surveillance Study

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Clinical trials have demonstrated the efficacy and safety of guselkumab in patients with moderate‐to‐severe plaque psoriasis. Real‐world evidence for guselkumab in Korea is needed to establish drug safety and effectiveness under real‐world practice in this population.
Bong Seok Shin   +13 more
wiley   +1 more source

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