Results 1 to 10 of about 27,161 (265)

A real-world pharmacovigilance study of romidepsin based on FDA adverse event reporting system database [PDF]

Frontiers in Oncology
BackgroundRomidepsin is a class I-selective histone deacetylase (HDAC) inhibitor indicated for the treatment of adult patients with cutaneous T-cell lymphoma (CTCL) who have received at least one prior systemic therapy and for adult patients with ...
Yuqin Yang, Yaping Huang, Yifan Wang, Yan Chen, Chengjie Ke, Chengjie Ke, Maohua Chen   +6 more
doaj   +2 more sources

Vitiligo secondary to immunosuppressants: a pharmacovigilance study of the FDA Adverse Event Reporting System [PDF]

Frontiers in Immunology
BackgroundVitiligo is an acquired depigmentation disorder affecting individuals worldwide. The potential link between immunosuppressants and the onset or exacerbation of vitiligo remains a topic of clinical concern.ObjectiveThis study aims to evaluate ...
Ying Jia, Hanzhang Xie, Yixuan Yang, Bingnan Cui, Junhui Wang, Zhanshuo Xiao   +5 more
doaj   +2 more sources

A study on the pharmacovigilance of various SGLT-2 inhibitors

Frontiers in Medicine
BackgroundSodium-glucose co-transporter two inhibitors (SGLT2is) are widely used in clinical practice due to their proven cardiovascular and renal benefits. However, various adverse drug reactions (ADRs) have been reported. This study aims to systematically update the ADRs associated with SGLT2is and identify the differences among various SGLT2is ...
Yanwen Dong, Yangyang Wang, Yangyang Wang, Xiaomei Lan, Xiaomei Lan, Huiyan Zeng, Huiyan Zeng   +6 more
exaly   +4 more sources

Drug-associated porphyria: a pharmacovigilance study

Orphanet Journal of Rare Diseases, 2023
Abstract Background The potentially fatal attacks experienced by porphyria carriers are triggered by various porphyrinogenic drugs. However, determining the safety of particular drugs is challenging.
qi wang, ling jun zhuang, bing han, miao chen, bin zhao   +4 more
openaire   +3 more sources

Evaluation of Pharmacovigilance System in Iran [PDF]

International Journal of Health Policy and Management, 2022
BackgroundEvaluating a pharmacovigilance system helps identify its deficiencies and could facilitate measures to remedy and improve the quantity and quality of adverse drug reaction (ADR) reports and other opportunities for pharmacovigilance systems ...
Malahat Khalili, Hamid Sharifi, Bita Mesgarpour, Mehrnaz Kheirandish, Sten Olsson, Naghmeh Javidnikou, Ali Akbar Haghdoost   +6 more
doaj   +1 more source

Metabolic and Nutritional Disorders Following the Administration of Immune Checkpoint Inhibitors: A Pharmacovigilance Study

Frontiers in Endocrinology, 2022
BackgroundAlthough several metabolic and nutritional disorders (MNDs) have been reported in the recipients of immune checkpoint inhibitors (ICIs), these events have not been fully captured and comprehensively characterized in real-world population ...
Yinghong Zhai, Xiaofei Ye, Fangyuan Hu, Fangyuan Hu, Jinfang Xu, Xiaojing Guo, Xiang Zhou, Yi Zheng, Xinxin Zhao, Xiao Xu, Yang Cao, Yang Cao, Jia He, Jia He   +13 more
doaj   +1 more source

Cardiovascular Toxicities of Ibrutinib: A Pharmacovigilance Study Based on the United States Food and Drug Administration Adverse Event Reporting System Database

Pharmaceuticals, 2023
Background: Although ibrutinib has been widely used to treat haematological malignancies, many studies have reported associated cardiovascular events. These studies were primarily animal experiments and clinical trials.
Yi Zheng, Xiaojing Guo, Chenxin Chen, Lijie Chi, Zhijian Guo, Jizhou Liang, Lianhui Wei, Xiao Chen, Xiaofei Ye, Jia He   +9 more
doaj   +1 more source

A study on pharmacovigilance case processing

Journal of Innovations in Applied Pharmaceutical Science (JIAPS), 2022
Pharmacovigilance plays an vital role in modern technology which helps in monitoring and assessing the high-quality of Drugs, detection and stopping of any unfavorable outcomes of drugs. Pharmacovigilance starts with case processing: this involve safety data collection and coding, case management reporting and submission.
Anil Kumar Y, Divya A, Sayamma B, Karishma Sk, Ravi Kumar Konda, Santhosh Kumar Ch   +5 more
openaire   +1 more source

Anaphylactic risk related to omalizumab, benralizumab, reslizumab, mepolizumab, and dupilumab

Clinical and Translational Allergy, 2021
Background Monoclonal antibodies (mAbs) are novel, effective therapeutics for the treatment of inadequately controlled severe asthma. Knowledge of the anaphylaxis risks related to different mAbs is essential for their appropriate and safe administration.
Lisha Li, Zixi Wang, Le Cui, Yingyang Xu, Kai Guan, Bin Zhao   +5 more
doaj   +1 more source

Organisation of the Russian Pharmacovigilance System: Survey of Pharmacovigilance Officers

Безопасность и риск фармакотерапии, 2021
Ensuring the safety of pharmacotherapy is a priority of the national regulatory health policy and is enshrined in the international and federal legislation.
A. E. Krasheninnikov, A. V. Matveev, S. D. Marchenko   +2 more
doaj   +1 more source