Results 131 to 140 of about 1,567,614 (310)

Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller   +6 more
wiley   +1 more source

Gold/Prussian Blue-Based Nanocomposites with Dual Nanozyme Activities Exert a Synergistic Effect of Starvation Therapy and Sonodynamic Therapy in the Treatment of Liver Cancer

open access: yesInternational Journal of Nanomedicine
Shengnan Huang,1,2,* Chengzhi Song,3,* Tengyue Zhao,4,* Yefei Yang,4 Zhiwei Yao,4 Shaofeng Duan,5 Wanyi Chen,6 Lixian Li,6 Xiaogang Hu,6 Chunming Li,6 Yurong Hu4 1Academy of Chinese Medical Sciences, Henan University of Chinese ...
Huang S   +10 more
doaj  

Aspects of pharmaceutical care for patients with cephalgia in specialized neurology clinics

open access: yesРеальная клиническая практика: данные и доказательства
Objective. To determine the characteristics of pharmaceutical care for patients with headache in specialized neurology clinics.Materials and methods.
O. V. Reshetko   +3 more
doaj   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman   +9 more
wiley   +1 more source

Dosing Optimization of Lamotrigine in Peripregnancy Epilepsy Through PopPK Modelling and Simulation

open access: yesDrug Design, Development and Therapy
Jiping Huo,1,2,* Yilin Liu,3,* Jiayu Yang,1,2,* Meng Chen,4,* Li Yang,1 Lijun Wang,5 Dongjie Zhang,1 Tongtong Liu,1 Wanli Gao,5 Haibin Dai,4 Shenghui Mei,1,2 Zhigang Zhao1,2 1Department of Pharmacy, Beijing Tiantan ...
Huo J   +11 more
doaj  

APOM-project : a study of pharmacy practice [PDF]

open access: yes
In 1994, a Ph.D-study started regarding pharmacy, organization and management (APOM) in the Netherlands. The APOM-project deals with the structuring and steering of pharmacy organization.
Mobach, Mark P.   +2 more
core   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler   +20 more
wiley   +1 more source

Simultaneous Determination of Venetoclax and Posaconazole in Human Plasma by UPLC-MS/MS: Application to Therapeutic Drug Monitoring in Acute Myeloid Leukemia Patients

open access: yesDrug Design, Development and Therapy
Xiaohai Chen,* Hualu Wu,* Haoxin Fu, Peiqi Wang, Lu Cao, Ruibin Li, Ruanjuan Zhan, Ren-Ai Xu Department of Pharmacy, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China*These ...
Chen X   +7 more
doaj  

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel   +8 more
wiley   +1 more source

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