Results 111 to 120 of about 1,234,322 (256)
Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan +7 more
wiley +1 more source
Shengnan Huang,1,2,* Chengzhi Song,3,* Tengyue Zhao,4,* Yefei Yang,4 Zhiwei Yao,4 Shaofeng Duan,5 Wanyi Chen,6 Lixian Li,6 Xiaogang Hu,6 Chunming Li,6 Yurong Hu4 1Academy of Chinese Medical Sciences, Henan University of Chinese ...
Huang S +10 more
doaj
Student yearbook of the New Jersey College of Pharmacy of Rutgers UniversityThe title of the College of Pharmacy Yearbook changed several times. The RX-Ray precedes the incorporation of the New Jersey College of Pharmacy into Rutgers in 1927.
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Posterior Disconnection Syndrome in Early‐Stage Adult‐Onset Cerebral Adrenoleukodystrophy
ABSTRACT Adult‐onset cerebral adrenoleukodystrophy is potentially treatable but often difficult to recognize before advanced cerebral involvement. Herein, we describe three men with early‐stage disease who initially presented with subtle visual complaints rather than subcortical dementia. Targeted neuropsychological testing revealed higher‐order visual
Kazuto Katsuse +13 more
wiley +1 more source
Dosing Optimization of Lamotrigine in Peripregnancy Epilepsy Through PopPK Modelling and Simulation
Jiping Huo,1,2,* Yilin Liu,3,* Jiayu Yang,1,2,* Meng Chen,4,* Li Yang,1 Lijun Wang,5 Dongjie Zhang,1 Tongtong Liu,1 Wanli Gao,5 Haibin Dai,4 Shenghui Mei,1,2 Zhigang Zhao1,2 1Department of Pharmacy, Beijing Tiantan ...
Huo J +11 more
doaj
Daftar Pengelola dan Daftar Isi
Daftar Pengelola dan Daftar Isi Pharmacy Vol. 13 No.
Pharmacy, Admin
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ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno +19 more
wiley +1 more source
Xiaohai Chen,* Hualu Wu,* Haoxin Fu, Peiqi Wang, Lu Cao, Ruibin Li, Ruanjuan Zhan, Ren-Ai Xu Department of Pharmacy, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China*These ...
Chen X +7 more
doaj
Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son +3 more
wiley +1 more source

