Results 61 to 70 of about 1,234,322 (256)

Threonine 348 regulates the subcellular localization of PTEN

open access: yesFEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

From Laboratory to Clinic: Translational Medicine Paradigm of Polymyxin B Nanopreparations for Overcoming Drug-Resistant Bacterial Infections

open access: yesInternational Journal of Nanomedicine
Na Li, Yong Cao, Ming Li, Dan Zheng, Wen Zhong, Chengli Yang Department of Pharmacy, Guizhou Key Laboratory of Integrated Traditional Chinese and Western Medicine, The Affiliated Hospital of Guizhou Medical University, Guiyang, 550004, People’s Republic ...
Li N   +5 more
doaj  

Indeks dan Panduan Penulis Pharmacy Vol. 15 No. 02 Desember 2018

open access: yes, 2018
Indeks dan Panduan Penulis Pharmacy Vol. 15 No.
(Pharmaceutical Journal Of Indonesia), PHARMACY: Jurnal Farmasi Indonesia
core  

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Indeks dan Panduan Penulis Pharmacy Vol. 15 No. 01 Juli 2018

open access: yes, 2018
Indeks dan Panduan Penulis Pharmacy Vol. 15 No.
(Pharmaceutical Journal Of Indonesia), PHARMACY: Jurnal Farmasi Indonesia
core  

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

open access: yesFEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa   +4 more
wiley   +1 more source

Pharmacy Newsletter : September 2014 [PDF]

open access: yes, 2014
Content: Pharmacy managed Polio immunization services FDA Pharmacy News Flash New weapons against MRSA Pencillin allergy and cross reactivity among beta lactams Inhales at Aga Khan University Hospital pharmacy services Proud to reporthttps://ecommons ...
Pharmacy Department,
core   +2 more sources

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

open access: yesFEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page   +4 more
wiley   +1 more source

Indeks Pharmacy Desember 2024

open access: yes
Indeks Pharmacy Desember ...
(Pharmaceutical Journal Of Indonesia), PHARMACY: Jurnal Farmasi Indonesia
core  

Ultrafast visual detection of Streptococcus suis via HtpsC‐targeted LAMP–CRISPR–Cas12a coupled with lateral flow immunochromatography

open access: yesFEBS Open Bio, EarlyView.
A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li   +7 more
wiley   +1 more source

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