Results 161 to 170 of about 199,848 (253)

Assessing resilience in pharmacy education during the COVID-19 era. [PDF]

Sci Rep
Al-Haqan A, Bates I, Almanasef M, Bajis D, Alnahar SA.   +4 more
europepmc   +1 more source

Caveolin‐1 Stabilizes SERCA2 to Counteract Acute Kidney Injury via Suppression of Ca2+‐Dependent Endoplasmic Reticulum Stress in Distal Tubules

Advanced Science, EarlyView.
In AKI, initial kidney injury upregulates the expression of Cav‐1, which subsequently binds to and stabilizes SERCA2 via its scaffolding domain and through deubiquitination, thereby regulating Ca2+ homeostasis and ER stress. Conversely, Cav‐1 deficiency accelerates SERCA2 degradation, triggering Ca2+ overload and ER stress, and ultimately exacerbating ...
Yan Zhang, Xin He, Hao Huang, Rong Lu, Xin Lv, Shenglan Li, Sijue Zou, Jiawei Cheng, Yiwei Xiong, Zhenghao Deng, Qiongjing Yuan, Yanyun Xie, Ling Huang, Jiaxi Pu, Shao Liu, Qianbin Li, Jie Meng, Huixiang Yang, Lijian Tao, Zhangzhe Peng   +19 more
wiley   +1 more source

Developing Professional Identity Through a Student-Led Interprofessional Clinic: A Qualitative Study in Experiential Pharmacy Education. [PDF]

J Med Educ Curric Dev
Valkonen V.
europepmc   +1 more source

N‐Doping Activated Presodiation Enhances Sodium‐Ion Provision in Hard Carbon Anodes

Advanced Science, EarlyView.
Introducing pyrrolic‐N sites enables efficient presodiation and stronger PF6− capture, thus pre ‐ forming a robust inorganic‐rich SEI layer in hard carbon anodes. ABSTRACT Hard carbon (HC) is considered the most promising anode material for commercial sodium‐ion batteries (SIBs), yet it still faces critical challenges such as low initial Coulombic ...
Hua Lin, Wenxing Miao, Yanrong Shi, Guangyi Mao, Ding Ding, Jian Weng, Zhongxiong Fan, Qingchi Xu, Jun Xu   +8 more
wiley   +1 more source

Assessment of cultural competence in pharmacy students before and after social and behavioural pharmacy education - a cross-sectional study. [PDF]

BMC Med Educ
Alfageh BH, Alsabhan JF, Aljadeed R, Alrasheed MA, Alshammari TK.   +4 more
europepmc   +1 more source

Drug‐Induced Cuproptosis Defines the Therapeutic Window of Celecoxib in Intervertebral Disc Degeneration via the HSP90‐RBX1 Axis

Advanced Science, EarlyView.
This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo, Hongju Xiao, Shenghao Ba, Yu Zhou, Bijun Wang, Bin Yu, Yufeng Huang, Haihong Zhao, Zhefan Stephen Chen, Na Shen, Zhaoyu Ba, Desheng Wu   +11 more
wiley   +1 more source

Building the U.S.-ASEAN Consortium for Pharmacy Education based on the U.S.-Thai Consortium experience: a qualitative study. [PDF]

J Pharm Policy Pract
Sookaneknun Olson P, Nathisuwan S, Katz MD, Srimongkon P, Jungnickel PW, Ploylearmsang C, Leelathanalerk A, Ryan M, Doungngern T, Oderda GM, Lau AH, Pattharachayakul S, Wattanachai P, Nimworapan M, Seesin T, Potisarach P.   +15 more
europepmc   +1 more source

SERRATE Regulates Floral Meristem Activity by Antagonizing SHOOT MERISTEMLESS and Repressing Cytokinin Signaling

Advanced Science, EarlyView.
Floral meristem (FM) activity is crucial for the initiation of floral organs. In this study, SE represses IPT7 expression and cytokinin signaling via both the miR171c‐5p–KNAT2 and miR164c–CUC1/2–KNAT2 regulatory modules, thereby repressing FM activity. In contrast, STM induces both KNAT2 and IPT7 expression.
Wen Yang, Yiting Wang, Yuxin You, Zhiyue Wu, Dongbao Li, Xin Wang, Yongsheng Chang, Hang Zhao, Tao Zhu, Dijun Chen, Wei Chen, Bo Sun   +11 more
wiley   +1 more source

Integrating large language models into clinical pharmacy education: applications in perioperative medication management for gastric cancer. [PDF]

Front Med (Lausanne)
Wang Y, Luan S, Shang N, Zhang X, Li Q.
europepmc   +1 more source

Pathogen‐Centric Activation of an Azoreductase‐Responsive Antibody‐Antibiotic Conjugate for the Targeted Eradication of MRSA

Advanced Science, EarlyView.
A pathogen‐centric antibody‐antibiotic conjugate (AZO‐AAC) releases antibiotics via bacterial azoreductase, independent of host‐lysosomal function. This mechanism achieves nanomolar eradication of both planktonic and intracellular methicillin‐resistant Staphylococcus aureus (MRSA).
Qi Cheng, Lianqi Liu, Chenghua Liu, Fei Xie, Jingwen Dong, Xiaoyu Qin, Shunxiang Huang, Xian Li, Xingyuan Kou, Hongbin Deng, Jiannan Feng, Wu Zhong, Dian Xiao, Xinbo Zhou   +13 more
wiley   +1 more source