Results 331 to 340 of about 6,441,578 (375)
Advanced Healthcare Materials, EarlyView.This study presents a multiphasic bile duct construct composed of biocompatible materials and cells, featuring an inner layer that supports biliary epithelium growth, a middle layer providing mechanical strength, and an outer cell‐permissive layer designed to support future in vivo integration.
Mattia Pasqua +9 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Imiquimod‐loaded nanoparticles (PFSUV‐IMQ) are found to decrease liver metastasis and liver tumor burden when administered intravenously. Flow cytometry, RNA‐seq and various experiments show that the anti‐tumor response is immune‐mediated by activating dendritic cells resulting in increased CD8 T cell infiltration and activity.
Vanessa Chan +13 more
wiley +1 more source
Ultra‐Tiny Gelatin Nanoparticles‐Assisted 3D Stem Cell Spheroids for Engineering Tissue Regeneration
Advanced Healthcare Materials, EarlyView.GNPs effectively guide the formation of structurally compact and functionally enhanced stem cell spheroids. This GNP‐assisted 3D culture system improves cell–cell and cell‐ECM interactions, leading to superior viability and complexity. Time‐dependent regenerative potential is demonstrated in both bone and skin defects, positioning GNP‐spheroids as a ...
Dream Kim +7 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Granular hydrogels are emerging microporous platforms for cell culture and delivery, showing great potential for replicating the complex, heterogeneous environments found in natural tissues. This review outlines the design principles of granular hydrogels, highlighting critical factors that determine the final physicochemical properties of the entire ...
Shuhan Feng, Kaiyang Chen, Shiqi Wang
wiley +1 more source
Pharmacy Internship - OpportunitiesIn Pharmacy Practice
The European Proceedings of Social and Behavioural Sciences, 2019 openaire +1 more source
Advanced Healthcare Materials, EarlyView.This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah +9 more
wiley +1 more source
Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases
Advanced Healthcare Materials, EarlyView.This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun +9 more
wiley +1 more source
Synthetic Aspects and Characterization Needs in MOF Chemistry – from Discovery to Applications
Advanced Materials, EarlyView.Overcoming the challenges of phase discovery, synthesis optimization and scale‐up, characterization, and computational studies is essential to accelerate the large‐scale application of MOFs. Life‐cycle analyses and techno‐economic analyses need to be performed to realistically assess their potential for industrial relevance.
Bastian Achenbach +4 more
wiley +1 more source
Advancing from MOFs and COFs to Functional Macroscopic Porous Constructs
Advanced Materials, EarlyView.This review study investigates the recent progress and methodologies for manufacturing metal–organic framework (MOF) or covalent–organic framework (COF)‐based 3D structured macroscopic porous constructs with high structural integrity, providing the possibility to control their porosity across dimensions.
Seyyed Alireza Hashemi +8 more
wiley +1 more source
Covalent Organic Frameworks for Photocatalysis
Advanced Materials, EarlyView.This review provides an overview of recent advances in covalent organic frameworks (COFs) for photocatalysis, focusing on sustainable energy applications like water splitting, hydrogen peroxide generation, and CO2 and N2 reduction. It discusses design principles, structure‐function relationships, challenges in COF photocatalysis, and strategies to ...
Bikash Mishra +6 more
wiley +1 more source