Results 81 to 90 of about 32,696 (196)

Streptococcus pyogenes pharyngitis elicits diverse antibody responses to key vaccine antigens influenced by the imprint of past infections

Nature Communications
Knowledge gaps regarding human immunity to Streptococcus pyogenes have impeded vaccine development. To address these gaps and evaluate vaccine candidates, we established a human challenge model of S. pyogenes pharyngitis.
Joshua Osowicki, Hannah R. Frost, Kristy I. Azzopardi, Alana L. Whitcombe, Reuben McGregor, Lauren H. Carlton, Ciara Baker, Loraine Fabri, Manisha Pandey, Michael F. Good, Jonathan R. Carapetis, Mark J. Walker, Pierre R. Smeesters, Paul V. Licciardi, Nicole J. Moreland, Danika L. Hill, Andrew C. Steer   +16 more
doaj   +1 more source

Assessing the Diagnostic Accuracy and Validity of the Mcisaac Modified Centor Score in Predicting Group A Beta Hemolytic Streptococcal Pharyngitis in A Trial to End Antibiotic Abuse in Children

SVU - International Journal of Medical Sciences
Background: Overuse of antibiotics leads to resistance. Pharyngitis is commonly viral but Group A Streptococcus (GAS) as a significant bacterial cause. GAS infections include suppurative and non-suppurative. Centor criteria assess GAS infection.
Usama Taya , Mai Abonewair , Amal Hosni, Alyaa Hassan Abo-Rahma, Nehad Hassan AbdElrhaman   +4 more
doaj   +1 more source

Age‐Dependent Differences in Canakinumab Safety: A Comprehensive Pharmacovigilance Analysis Using the FAERS Database

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT While the efficacy of canakinumab, an anti‐interleukin‐1β monoclonal antibody, is well‐established, its safety profile, particularly across different age groups, remains inadequately explored. Using the FDA Adverse Event Reporting System (FAERS) database, this study evaluated postmarketing safety by analyzing adverse event (AE) reports from ...
Youyang Wang, Ngasin Lam, Xiaoming Huang, Yang Jiao   +3 more
wiley   +1 more source

Harnessing Trace Elements: Novel Radiosensitization Strategies for Enhanced Cancer Radiotherapy

Rare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT Radiotherapy (RT) is one of the core methods of comprehensive cancer treatment. Globally, more than 40% of cancer patients rely on radiotherapy to achieve tumor control, cure or palliative relief. However, radiation resistance, immunosuppression and normal tissue injury limit its clinical application.
Yuhuan Zhang, Yizhi Ge, Hongguang Xiang, Ji Liu, Yu Tian, Yan Shen, Dan Zong   +6 more
wiley   +1 more source

Comparative Study Between Integrated Management of Childhood Illness Guidelines and Traditional Methods in Management of Acute Pharyngitis among Children Under Five Years in Zagazig District, Egypt

Journal of High Institute of Public Health, 2018
Background: Pharyngitis is one of the most frequently faced pediatric problems with serious complications in primary care. Objective(s): To compare between Integrated Management of Childhood Illness (IMCI) guidelines and traditional management ...
Abdalla H. M. Elsharkawy, Ghada M. Salem, Amel E. Mohamed, Maha S. Eltwansy   +3 more
doaj   +1 more source

The sore throat: a clinical approach to tonsillopharyngitis

South African Family Practice, 2019
Acute sore throat is a common complaint encountered by medical practitioners and health care workers routinely. The disease is mostly caused by viral infections of the upper respiratory tract and is usually self-limiting. Symptoms rarely exceed two weeks,
A. Marais, M. Leuschner
doaj   +1 more source

Solitary Neurofibroma of the Hypopharynx: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
Matin Ghazizadeh, Vahid Ghasem Amooeian
wiley   +1 more source

Modulation of Quorum Sensing and Virulence Gene Expression in Escherichia coli by Extracts of Physalis alkekengi

Environmental Microbiology Reports, Volume 18, Issue 3, June 2026.
Root extracts of Physalis alkekengi were examined for activity against multidrug‐resistant (MDR) Escherichia coli. The ethanolic extract suppressed bacterial growth, lowered biofilm formation by ~63%, and markedly reduced expression of luxS and fimH. Findings highlight P.
Mansoureh Esfandiyari Doolaby, Mohammad Javad Mehdipour Moghaddam, Akbar Norastehnia   +2 more
wiley   +1 more source

Constitutional symptoms and response to Penicillin G in erysipelas and cellulitis – a monocentric, retrospective, explorative study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 6, Page 746-754, June 2026.
Summary Background: Erysipelas, caused by streptococci, should be treated with penicillin, while uncomplicated cellulitis (phlegmon), often caused by Staphylococcus aureus, requires penicillinase‐resistant beta‐lactam antibiotics, which have a higher risk of adverse effects. Distinguishing between these infections is important.
Helena Schieffers, Cord Sunderkötter
wiley   +1 more source

The combined manifestations of dramatically sore throat, congested and edematous mucosa, no-swelling tonsil are specific in acute Omicron pharyngitis

BMC Infectious Diseases
Objective To identify specific clinical signs of Omicron pharyngitis infection. Methods A clinical cross-sectional retrospective study was designed to analyze the primary symptoms of pharyngitis in outpatients seeking treatment for sore throat ...
Lei Zhou, Lineng Zhang, Feng Xu
doaj   +1 more source