Results 91 to 100 of about 39,067 (230)

An Open‐Label Study Investigating the 5‐HT2A Receptor Occupancy of Remlifanserin (ACP‐204) With the PET Radioligand [18F]Altanserin in Healthy Male Participants

Clinical Pharmacology in Drug Development, Volume 15, Issue 9, September 2026.
Abstract Remlifanserin (ACP‐204) is a selective 5‐HT2A receptor inverse agonist that builds upon scientific findings of its structural analog, pimavanserin. This Phase 1, open‐label study in healthy adults (N = 16) describes the central 5‐HT2A receptor occupancy of remlifanserin at different doses and plasma concentrations using positron emission ...
Ethan S. Burstein, Christine Sandiego, Brian Raether, Xiaoshu Feng, Bryan Dirks, Mona Darwish, Peter Zhang, David S. Russell, Eugenii A. Rabiner, Sanjeev Pathak   +9 more
wiley   +1 more source

Streptococcal pharyngitis: Delving deeper than the throat [PDF]

, 2021
Acute rhabdomyolysis and elevated transaminases during streptococcal pharyngitis are rare presentations. The proposed pathophysiological mechanisms include direct bacterial invasion and toxin generation.
Sheikh, Sadaf, Baig, Muhammad Akbar, Javed, Umair   +2 more
core  

Human Metapneumovirus and Its Association With Otorhinolaryngological Manifestations: A Systematic Review With Descriptive Synthesis

Eye &ENT Research, Volume 3, Issue 3, Page 111-117, September 2026.
ABSTRACT Human metapneumovirus (HMPV) is a respiratory virus that predominantly affects the pediatric population. Its role as an infective agent in ear, nose, and throat (ENT) diseases is not yet well understood. To systematically review the available literature on the association between HMPV and ENT manifestations, following PRISMA guidelines, a ...
Ali Gohar, Muhammad Husnain Ahmad, Hamza Zaheer, Fizza Inam, Moeez Ahmad Saeed, Nimra Mehmood, Abdul Rehman Shahid Khan, Alishbah Saeed, Hanzala Zahid, Yashika Gupta, Muhammad Bilal Akram, Habban Ghani, Muhammad Ahmad Farooq   +12 more
wiley   +1 more source

Comparative Study Between Integrated Management of Childhood Illness Guidelines and Traditional Methods in Management of Acute Pharyngitis among Children Under Five Years in Zagazig District, Egypt

Journal of High Institute of Public Health, 2018
Background: Pharyngitis is one of the most frequently faced pediatric problems with serious complications in primary care. Objective(s): To compare between Integrated Management of Childhood Illness (IMCI) guidelines and traditional management ...
Abdalla H. M. Elsharkawy, Ghada M. Salem, Amel E. Mohamed, Maha S. Eltwansy   +3 more
doaj   +1 more source

A Multicenter, Open‐Label, Phase 2 Trial Comparing Crizanlizumab Combined With Standard Therapy to Standard Therapy Alone on Renal Function in Patients With Sickle Cell Nephropathy (STEADFAST)

American Journal of Hematology, Volume 101, Issue 10, Page 2666-2671, October 2026.
Kenneth I. Ataga, Pablo Bartolucci, Santosh L. Saraf, Vimal K. Derebail, Adlette Inati, Jeffrey D. Lebensburger, Laurie DeBonnett, Rodolfo D. Cancado, Claire C. Sharpe   +8 more
wiley   +1 more source

Pediatric Systemic Lupus Erythematosus Complicated by Acute EBV and CMV Co‐infection

Journal of Clinical Laboratory Analysis, Volume 40, Issue 17, September 2026.
This case report describes a 10‐year‐old girl with new‐onset pediatric SLE who presented with malar rash, fever, and arthritis following sun exposure, alongside serological evidence of acute Epstein–Barr virus (EBV) and cytomegalovirus (CMV) co‐infection.
Anning Chen, Gengchun Ji, Ziping Lan, Ping Li, Jianwei Wang, Le Zhang, Chaojun Hu, Shulan Zhang   +7 more
wiley   +1 more source

Pharyngeal entomophthoromycosis

Journal of the Chinese Medical Association, 2014
We describe a rare case of entomophthoromycosis of the pharynx in a previously healthy patient, unlike other fungal infections which are seen as opportunistic infections in immunocompromised hosts. This infection is commonly seen in subtropical and tropical areas of Africa, America, and Asia.
Yu, Wan-Nien, Chen, Chih-Jung, Chen, Chih-Ming   +2 more
openaire   +2 more sources

The combined manifestations of dramatically sore throat, congested and edematous mucosa, no-swelling tonsil are specific in acute Omicron pharyngitis

BMC Infectious Diseases
Objective To identify specific clinical signs of Omicron pharyngitis infection. Methods A clinical cross-sectional retrospective study was designed to analyze the primary symptoms of pharyngitis in outpatients seeking treatment for sore throat ...
Lei Zhou, Lineng Zhang, Feng Xu
doaj   +1 more source

A Controlled Human Infection Model of Group A Streptococcus Pharyngitis: Which Strain and Why?

mSphere, 2019
Group A Streptococcus (GAS) is a major cause of global infection-related morbidity and mortality. A modern controlled human infection model (CHIM) of GAS pharyngitis can accelerate vaccine development and pathogenesis research.
Joshua Osowicki, Kristy I. Azzopardi, Liam McIntyre, Tania Rivera-Hernandez, Cheryl-lynn Y. Ong, Ciara Baker, Christine M. Gillen, Mark J. Walker, Pierre R. Smeesters, Mark R. Davies, Andrew C. Steer   +10 more
doaj   +1 more source

Foreign body ingestions in children and adolescents: A position paper of the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) endoscopy special interest group

Journal of Pediatric Gastroenterology and Nutrition, Volume 83, Issue 3, Page 539-554, September 2026.
Abstract Foreign body (FB) ingestion is a relatively frequent occurrence in the pediatric population with multiple potential sequelae. Appropriate intervention may range from urgent endoscopic retrieval to watchful waiting, with multiple variables influencing the decision.
Oren Ledder, Raoul Furlano, Alexandra Papadopoulou, Dominique Schluckebier, Andreia Nita, Christos Tzivinikos, Salvatore Oliva, Simona Faraci, Luigi Dall'oglio, Marco Deganello Saccomani, Priya Narula, Iva Hojsak, Jorge Amil Dias, Vasiliki Spyropoulou, Lorenzo Norsa, Gokhan Baysoy, Claudio Romano, Matjaž Homan, Mike Thomson   +18 more
wiley   +1 more source