Results 111 to 120 of about 3,406,941 (299)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Phase Change Material with Gelation Imparting Shape Stability

ACS Omega, 2022
Gleb Vasilyev, Naama Koifman, Michael Shuster, Michael Gishvoliner, Yachin Cohen, Eyal Zussman   +5 more
doaj   +1 more source

Phase Change Material Device for Spacecraft Thermal Control [PDF]

, 2011
On board a satellite, the experiments and subsystems have to be maintained within specified temperature limits. Phase Change Materials (PCM) offer the possibility to store thermal energy directly as latent heat of fusion.
Collette, Jean-Paul, Crahay, Jean, Larnicol, Maïwenn, Nutal, Nicolas, Peyrou-Lauga, R., Pin, O., Rochus, Pierre   +6 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Thermal modeling of phase change solidification in thermal control devices including natural convection effects [PDF]

Natural convection effects in phase change thermal control devices were studied. A mathematical model was developed to evaluate natural convection effects in a phase change test cell undergoing solidification.
Golden, J. O., Stermole, F. J., Ukanwa, A. O.   +2 more
core   +1 more source

Phase‐Change and Ovonic Materials (Second Edition) [PDF]

physica status solidi (RRL) – Rapid Research Letters, 2021
Noé, Pierre, Kooi, Bart J., Wuttig, Matthias   +2 more
openaire   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Some remarks about pseudo gap behavior of nearly antiferromagnetic metals

, 2001
In the antiferromagnetically ordered phase of a metal, gaps open on parts of the Fermi surface if the Fermi volume is sufficiently large. We discuss simple qualitative and heuristic arguments under what conditions precursor effects, i.e. pseudo gaps, are
A. Abanov, A. Chubukov, A. Rosch, A. Rosch, A. Rosch, A. Rosch, A. Schröder, A. Schröder, A.J. Millis, A.J. Millis, A.P. Kampf, A.V. Chubukov, Ar. Abanov, B.I. Shraiman, C. Kübert, D. Belitz, D. Belitz, D. Belitz, H.v. Löhneysen, H.v. Löhneysen, J. Schmalian, J. Schmalian, J.A. Hertz, J.L. Smith, J.R. Schrieffer, L. Balents, L. Bartosch, L. Bartosch, L. Bartosch, O. Stockert, P. Monthoux, Q. Si, R. Preuss, S. Moukouri, S.A. Brazovskii, T. Senthil, Y.M. Vlik, Y.M. Vlik   +37 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source