Results 91 to 100 of about 950,232 (298)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Performance of Equal Phase-Shift Search for One Iteration

, 2007
Grover presented the phase-shift search by replacing the selective inversions by selective phase shifts of $\pi /3$. In this paper, we investigate the phase-shift search with general equal phase shifts.
144, 292, 362, arXiv:quant-ph/9605034, Brassard, D. Li, Grover, Grover, H. Huang, J. P. Chen, Roland, Tulsi, X. Li, X. Li   +13 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

PHASE ANGLE SHIFT AND SLOPE BASED RESTRAINT FOR INDIRECT SYMMETRICAL PHASE SHIFT TRANSFORMER PROTECTION

Journal of Engineering and Sustainable Development
This study presents a method to limit the functioning of the differential relay during the different operating conditions of an Indirect Symmetrical Phase Shift Transformer (ISPST).
Shailendra Kumar Bhasker, Manoj Tripathy
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Perancangan Sistem Modulator Binary Phase Shift Keying

Techne, 2016
Sistem yang dibangun adalah sebuah modul sistem modulator BPSK (Binary Phase Shift Keying). Perangkat yang dibahas adalah modulator BPSK dengan frekuensi 10kHz-48kHz dan untuk transmisi secara nirkabel ditambahkan pemancar FM yang akan mentranslasikan ...
Deddy Susilo, Budihardja Murtianta, Arivia Aurelia Devina P.   +2 more
doaj   +1 more source

Geometric phase shift for detection of gravitational radiation

, 2004
An effect of geometrical phase shift is predicted for a light beam propagating in the field of a gravitational wave. Gravitational radiation detection experiments are proposed using this new effect, the corresponding estimates being given.Comment ...
Mitskievich, N V, Nesterov, A I
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Anomalous phase shift in a twisted quantum loop

, 2010
Coherent motion of electrons in a twisted quantum ring is considered to explore the effect of torsion inherent to the ring. Internal torsion of the ring composed of helical atomic configuration yields a non-trivial quantum phase shift in the electrons ...
Barwick B, Bohm A, Chaplik A V, Cotaescu I I, Hiroyuki Shima, Hisao Taira, Imry Y, Imry Y, McIlroy D N, Schwingenschlögl U, Shima H, Taira H, Taira H   +12 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source