Results 101 to 110 of about 950,232 (298)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

EFFECT OF PHASE-SHIFT INTERFERENCE ON THE NOISE IMMUNITY OF CORRELATION DEMODULATOR OF SIGNALS WITH MULTIPLE PHASE SHIFT KEYING

open access: yesРоссийский технологический журнал, 2019
The energy and spectral advantages of signals with phase shift keying predetermined their widespread use in modern digital navigation, communications and television systems. The use of such signals is the base of communication standards of DVB-S, DVB-S2 /
Gennady V. Kulikov   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Detecting the Extremely Small Angle of an Axicon by Phase-Shifting Digital Holography

open access: yesApplied Sciences, 2019
Axicon is an optical element that can be used to produce high-quality Bessel beams efficiently. In general, the smaller the base angle of the axicon is, the longer the diffraction-free distance of the generated Bessel beam will be. Therefore, axicon with
Yuchuan Zheng   +5 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Variable phase equation in quantum scattering

open access: yesRevista Brasileira de Ensino de Física
This paper presents the derivation and applications of the variable phase equation for single channel quantum scattering. The approach was first presented in 1933 by Morse and Allis and is based on a modification of the Schrödinger equation to a first ...
Vitor D. Viterbo   +2 more
doaj   +1 more source

Plasmon Geometric Phase and Plasmon Hall Shift

open access: yesPhysical Review X, 2018
The collective plasmonic modes of a metal comprise a simple pattern of oscillating charge density that yields enhanced light-matter interaction.
Li-kun Shi, Justin C. W. Song
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Focusing and phase compensation of paraxial beams by a left-handed material slab

open access: yes, 2006
On the basis of angular spectrum representation, a formalism describing paraxial beams propagating through an isotropic left-handed material (LHM) slab is presented.
Born   +40 more
core   +1 more source

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