Results 101 to 110 of about 39,265 (303)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Nonlinear Silicon Photonic Signal Processing Devices for Future Optical Networks

open access: yesApplied Sciences, 2017
In this paper, we present a review on silicon-based nonlinear devices for all optical nonlinear processing of complex telecommunication signals. We discuss some recent developments achieved by our research group, through extensive collaborations with ...
Cosimo Lacava   +2 more
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

KINERJA MODULASI DIGITAL DENGAN METODE PSK(PHASE SHIFT KEYING) [PDF]

open access: yes, 2011
Informasi dan telekomunikasi sebagai salah satu kebutuhaan masyarakat modern mengalami perkembangan yang sangat cepat, informasi akan dapat tersebar luas, dapat diterima dengan cepat, serta memberikan kepuasan pada penerimanya.
Hapsara, Agha Kurniawan   +2 more
core  

Quadrature‐carrier amplitude phase shift keying

open access: yesIET Communications, 2019
Amplitude phase shift keying (APSK) is the emerging modulation scheme used in deep satellite communications and known to have a high spectral and energy efficiency among other two‐dimensional (2‐D) M‐ary schemes.
Abdulkerim Öztekin, Ergun Erçelebi
openaire   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Multi-Channel Parallel Mode Shift Keying Secure Communication System Based on Multi-Mode Chaotic Laser Synchronization

open access: yesIEEE Photonics Journal
This paper proposes a multi-channel parallel mode shift keying secure communication scheme based on multi-mode chaotic laser synchronization, aiming to address the issues of structural complexity and low transmission rates in traditional chaos shift ...
Yuehua An   +3 more
doaj   +1 more source

Performance of DPSK Signals with Quadratic Phase Noise

open access: yes, 2004
Nonlinear phase noise induced by the interaction of fiber Kerr effect and amplifier noises is a quadratic function of the electric field. When the dependence between the additive Gaussian noise and the quadratic phase noise is taking into account, the ...
Ho, Keang-Po
core   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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