Results 101 to 110 of about 940,971 (329)
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Asymptotic security of continuous-variable quantum key distribution with a discrete modulation
, 2019 We establish a lower bound on the asymptotic secret key rate of continuous-variable quantum key distribution with a discrete modulation of coherent states.
Diamanti, Eleni +3 more
core +3 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
On the Feasibility of Efficient Multiamplitude Communication [PDF]
Bandwidth constraints in earth-satellite communication systems force consideration of uncoded M-ary modulation to obtain increased data rates. M-ary phase shift keying (MPSK) at first glance seems most promising because of the high transmitter efficiency
Smith, J. G.
core +1 more source
General Analysis of Switching Modes in a Dual Active Bridge with Triple Phase Shift Modulation
Energies, 2018 This paper provides an exhaustive analysis of the Dual-Active-Bridge with Triple-Phase-Shift (DAB-TPS) modulation and other simpler ones, identifying all the possible switching modes to operate the DAB in both power flow directions, and for any input-to ...
C. Calderón +6 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Large phase modulation of THz wave via an enhanced resonant active HEMT metasurface
Nanophotonics, 2018 Terahertz (THz) science and technology promise unique applications in high-speed communications, high-accuracy imaging, and so on. To keep up with the demand for THz systems, THz dynamic devices should feature large phase shift modulation and high speed.
Zhang Yaxin +13 more
doaj +1 more source
IEEE Journal of Emerging and Selected Topics in Power Electronics, 2018 This paper proposes a fundamental frequency sorting algorithm for balancing the floating capacitors in modular multilevel converters with low-frequency carrier phase shift modulation.
Guipeng Chen +4 more
semanticscholar +1 more source