Results 171 to 180 of about 15,413,531 (300)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Effective Demand and Income Distribution in The General Theory

, 1994
The paper looks at income distribution in a short-period context which is similar to that of Keynes’s General Theory. The approach to distribution is different from the one Kaldor adopted in the 1950s: no assumption of full employment is made.
Sardoni, C.
core  

Global inequities in representation of low-income and middle-income countries in vaccine clinical trials: protocol for a systematic review and meta-epidemiological analysis. [PDF]

BMJ Open
Ramalan M, Yusuf I, Mathew M, Bako I, Imam MU, Musa B.   +5 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

The Early Marginalists and the Transformation of Distribution Theory

, 1992
This paper examines the roles of Jevons, Menger and Walras in transforming distribution theory from the analysis of a social issue into a subset of general price theory.
Baum, S.
core  

Cell competition driven by secreted ligands: Modeling liver metastasis of colorectal cancer. [PDF]

Proc Natl Acad Sci U S A
Nemati H, Suijkerbuijk SJE, de Graaf J.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Pore-scale modelling of methane-driven helium extraction in deep tight sandstones. [PDF]

Sci Rep
Zhao H, Zhang B, Zhang J, Liu L, Yang Y, Zhou Y, Kang R.   +6 more
europepmc   +1 more source

On the Properties of Acyclic Bilateral Phase Type Distributions [PDF]

Proceedings of the 2nd International ICST Conference on Performance Evaluation Methodologies and Tools, 2007
HORVATH, Andras, M. TELEK
openaire   +2 more sources

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source