Results 131 to 140 of about 11,382,550 (291)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Multivariate Phase-type Distributions in Stochastic Modelling

This thesis concerns univariate and multivariate phase-type distribution with a focus on their usage in statistics. Chapters 1-3 serve as motivation and an introduction to the subject.
Gardner, Clara Brimnes
core  

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Cluster-based fitting of phase-type distributions to empirical data

We present a clustering-based fitting approach for phase-type distributions that is particularly suited to capture common characteristics of empirical data sets.
Krauss T, Reinecke P, Wolter K
core   +4 more sources

On the Spatial Distribution of Luminous Blue Variables, B[e] Supergiants, and Wolf–Rayet Stars in the Large Magellanic Cloud

The Astrophysical Journal
We examine the spatial distributions of luminous blue variables (LBVs), B [ e ] supergiants, and Wolf–Rayet stars (WR) stars in the Large Magellanic Cloud (LMC) to clarify their relative ages, evolutionary states, and relationships. This survey employs a
John C. Martin, Roberta M. Humphreys, Kris Davidson   +2 more
doaj   +1 more source

Convolutions of multivariate phase-type distributions

This paper is concerned with multivariate phase-type distributions introduced by Assaf et al. (1984). We show that the sum of two independent bivariate vectors each with a bivariate phase-type distribution is again bivariate phase-type and that this is ...
Hipp, Christian, Berdel, Jasmin
core  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Numerical Simulation of New Types Mechanical Filter Structure Used for the Railway Vehicles

机车电传动, 2015
Based on the analysis of the usual used GL mechanical filter, three new types of mechanical filters were put forward. The two dimension cyclic symmetric geometry model was built, and combined SIMPLE algorithm with the Realizable k-ε turbulent model and ...
WANG Weibin, LIN Peng, CHEN Dawei, LIU Shaoqing   +3 more
doaj  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Efficient sampling from phase-type distributions

Operations Research Letters
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources