Results 141 to 150 of about 137,818 (293)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Planar waveguides can be written with a UV-laser into photosensitised silica to produce a wide range of optical devices. Careful modulation of two interfering beams allows Bragg gratings to be directly written into the channel.
Grossel, M.C. +3 more
core +1 more source
A Biologically-Inspired Clustering Algorithm Dependent on Spatial Data in Sensor Networks. [PDF]
, 2005 Sensor networks in environmental monitoring applications aim to provide scientists with a useful spatio-temporal representation of the observed phenomena.
Marshall, Ian +3 more
core
Design of biological sensors based on the OpvAB phase variation system of Salmonella enterica
, 2020 Este trabajo se ha basado en investigaciones previas de nuestro grupo sobre el operón opvAB de Salmonella enterica y ha utilizado dichos conocimientos para diseñar y desarrollar tres aplicaciones biotecnológicas: (i) la formación de subpoblaciones bacterianas que difieran en un fenotipo específico elegido a voluntad, (ii) el desarrollo de un biosensor ...
openaire +2 more sources
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
, 2006 Fiber Bragg gratings have been demonstrated as a versatile sensor for structural health monitoring. We present an efficient and cost effective multiplexing method for fiber Bragg grating and fiber Fabry-Perot sensors based on a broadband mode-locked ...
Kirkendall, C. K. +2 more
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Teaching old sensors New tricks: archetypes of intelligence
, 2007 In this paper a generic intelligent sensor software architecture is described which builds upon the basic requirements of related industry standards (IEEE 1451 and SEVA BS- 7986). It incorporates specific functionalities such as real-time fault detection,
White, Neil M. +3 more
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source