Results 81 to 90 of about 127,919 (291)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Quantitative sensitivity analysis of surface attached optical fiber strain sensor [PDF]

, 2014
Optical fiber strain sensors, in particular, the fiber Bragg grating (FBG) type, are widely applied in different applications. The most common installation method is surface-attached.
Wan, KT
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Interferometric time division FBG interrogator and multiplexer with static, dynamic, and absolute wavelength measurement capabilities

, 2012
We report on the design and preliminary testing of an interferometric interrogator capable of large-scale time-division multiplexing of FBG sensors. The scheme employs a passive algorithm for phase demodulation, allowing changes in FBG sensor reflected ...
Philip Orr, Niewczas, Pawel, Paweł Niewczas, Alan Paterson, Paterson, Alan, Orr, Philip   +5 more
core   +1 more source

Control of Utility Interfacing Modular High Frequency AC Link Converter Based on Fundamental Current Estimation

IEEE Access
This work proposes a cell-to-cell voltage balance and flexible power sharing control strategy for 1-phase utility interfacing 1-phase modular high frequency AC link (HFAC-L) converter.
Gourahari Nayak, Anindya Dasgupta
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Efficient large-scale multiplexing of fiber Bragg grating and fiber Fabry-Perot sensors for structural health monitoring applications

, 2006
Fiber Bragg gratings have been demonstrated as a versatile sensor for structural health monitoring. We present an efficient and cost effective multiplexing method for fiber Bragg grating and fiber Fabry-Perot sensors based on a broadband mode-locked ...
Kirkendall, C. K., Flockhart, G. M. H., Cranch, Geoffrey A.   +2 more
core   +1 more source

Differential phase tracking applied to Bragg gratings in multi-core fibre for high accuracy curvature measurement [PDF]

, 2006
High resolution quasi-static and dynamic curvature measurements are made by differential interferometric phase measurement of fibre Bragg gratings in separate cores of a multi-core fibre.
Flockhart, G M H, Kirkendall, Clay K., Clay K. Kirkendall, Cranch, G A, Flockhart, Gordon M. H., Geoffrey A. Cranch, Kirkendall, C K, Gordon M. H. Flockhart, Cranch, Geoffrey A.   +8 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source