Results 111 to 120 of about 120,540 (303)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
A Qualitative Evaluation of Volunteers' Experiences in a Phase I/II HIV Vaccine Trial in Tanzania. [PDF]
, 2011 Evaluating experiences of volunteers in an HIV vaccine trial will be useful for the conduct of future trials. The purpose of this study among volunteers who participated in a phase I/II HIV vaccine trial in Dar es Salaam, Tanzania was to assess what ...
Thorson, Anna +20 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
An Optimal Bidding Strategy of Power and Gas to Operate a Microgrid in Energy Market [PDF]
Journal of Artificial Intelligence and System ModellingMicrogrids could lower their costs in the day-ahead market through bidding in a smart distribution network. The bidding dilemma is difficult because there are many uncertainties.
Nahia Diez, Ivan Loya
doaj +1 more source
Investigation of Three-Phase Balancing Techniques : A Comparative Study of Different Solutions With Respect to Telecom Industry Needs [PDF]
, 2020 In the telecom industry, one-phase rectifiers are commonly used in base stations and site power systems. The abundant of this one phase loads connected to the three-phase network where three-phase installations are required can enhance the amount of ...
Mahdee, Mahir
core
Output current balancing method for three-phase interleaved LLC resonant converter employing Y-connected rectifier [PDF]
, 2014 This paper presents the output current balancing method for three-phase interleaved full-bridge LLC resonant converter which employs a Y-connected rectifier.
Jee-Hoon Jung +5 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
A Method of Balancing Control for Capacitor Voltage of Modular Multilevel Converter
Kongzhi Yu Xinxi Jishu, 2012 This paper introduces the operation principle of modular multilevel converter and balancing control method of capacitor voltage. Considering the condition under external disturbance which may lead to outputting unbalanced voltage and waveform distortion ...
LI Yunfeng, SONG Pinggang, WANG Chu
doaj
Two-Phase Load Balancing for Data Center Networks using OpenFlow [PDF]
, 2018 This invited paper describes an OpenFlow solution for two-phase load balancing optimized for data center networks. The solution uses aggregate flows and Proxy ARP procedure in order to achieve reduced size of OpenFlow tables, fast flow configuration and ...
N. Maksić
core +1 more source