Results 61 to 70 of about 15,407,758 (296)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Research progress on solar energy storage water tanks based on phase-change materials

工程科学学报, 2023
In the field of building energy conservation, solar energy is a highly favored clean energy source. However, the instability and discontinuity of solar energy greatly affect its application. Phase-change energy storage technology is widely used for solar
Na HE, Guohui FENG, Tianyu WANG
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

A Modified Carbon Monofilament Effect on Shape Stability, Leakage Reduction, and Thermal Storage Efficiency of Phase Change System Based on Poly(ethylene glycol) [PDF]

علوم و تکنولوژی پلیمر
Hypothesis: Phase change materials (PCMs) can store latent heat energy during the phase change from solid to liquid. In previous studies, researchers have usually used the microencapsulation method to solve the leakage problem during melting.
Fateme Karimi Eskaboni, Golnoosh Abdeali, Azadeh Seifi, Ahmad Reza Bahramian   +3 more
doaj   +1 more source

Modelling of free boundary problems for phase change with diffuseinterfaces [PDF]

Mathematical Problems in Engineering, 2005
We present a continuum thermodynamical framework for simulating multiphase Stefan problem. For alloy solidification, which is marked by a diffuse interface called the mushy zone, we present a phase filed like formalism which comprises a set of macroscopic conservation equations with an order parameter which can account for the solid, liquid, and the ...
Sanyal, Dipayan, Rao, P. Ramachandra, Gupta, O. P.   +2 more
openaire   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Heat transfer enhancement for thermal energy storage using metal foams embedded within phase change materials (PCMs) [PDF]

, 2010
In this paper the experimental investigation on the solid/liquid phase change (melting and solidification) processes have been carried out. Paraffin wax RT58 is used as phase change material (PCM), in which metal foams are embedded to enhance the heat ...
Zhao, Changying, Lu, Wei, Tian, Yuan, Tian, Y. (Yuan), Zhao, C.Y., Lu, W   +5 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Detecting Output Pressure Change of Positive-Displacement Pump by Phase Trajectory Method [PDF]

Acta Montanistica Slovaca, 2010
The monitoring of hydraulic system condition change during its exploitation ran its complex problem. The main task is to identifyearly phase damage of hydraulic system elements (pumps, valves, ect.) in order to take decision which can avoid hydraulic ...
Jerzy Stojek
doaj  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source