Results 141 to 150 of about 568,779 (262)

Phase Diagram-Guided Molten Salt Engineering of Biocarbon Pores at Low Temperatures. [PDF]

Small
Yang P, Ma J, Yang K, Zhang D, Zhu P, Chen W, Bi X, Jiang F.   +7 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Magnetic Structures and Magnetic Phase Diagram of the Mixed-Valence Iron Phosphate Fe₇(PO₄)₆. [PDF]

Inorg Chem
Dönni A, Keller L, Pomjakushin VY, Tsujii N, Belik AA.   +4 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Phase diagram and spectroscopic signatures of a supersolid in the quantum ising magnet K₂Co(SeO₃)₂. [PDF]

Nat Commun
Chen T, Ghasemi A, Zhang J, Shi L, Tagay Z, Chen Y, Chen L, Choi ES, Jaime M, Lee M, Hao Y, Cao H, Winn BL, Podlesnyak AA, Pajerowski DM, Zhong R, Xu X, Armitage NP, Cava R, Broholm C.   +19 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Machine Learning simulations reveal oxygen's phase diagram and thermal properties at conditions relevant to white dwarfs. [PDF]

Nat Commun
Wang Y, Shi J, Liang Z, Huang T, Wang J, Ding C, Pickard CJ, Wang HT, Xing D, Ni D, Sun J.   +10 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Correlations in Magnetic Sub-Domains as an Unconventional Phase Diagram for van der Waals Ferromagnets. [PDF]

Adv Sci (Weinh)
Grebenchuk SY, Grzeszczyk M, Chen Z, Šiškins M, Borisov V, Pereiro M, Katsnelson MI, Eriksson O, Novoselov KS, Koperski M.   +9 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source