Results 81 to 90 of about 4,298,588 (299)
How Should We Use Colour in Euler Diagrams? [PDF]
, 2014 This paper addresses the problem of how best to use colour in Euler diagrams. The choice of using coloured curves, rather than black curves, possibly with coloured fill is often made in tools that automatically draw Euler diagrams for information ...
Howse, John +8 more
core +1 more source
Automated navigation of condensate phase behavior with active machine learning
Nature CommunicationsBiomolecular condensates are essential cellular structures formed via biomacromolecule phase separation. Synthetic condensates allow for systematic engineering and understanding of condensate formation mechanisms and to serve as cell-mimetic platforms ...
Yannick H. A. Leurs +8 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Machine-learned interatomic potentials for alloys and alloy phase diagrams
npj Computational Materials, 2021 We introduce machine-learned potentials for Ag-Pd to describe the energy of alloy configurations over a wide range of compositions. We compare two different approaches.
Conrad W. Rosenbrock +6 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Introducing 3D Venn and Euler Diagrams [PDF]
, 2012 In 2D, Venn and Euler diagrams consist of labelled simple closed curves and have been widely studied. The advent of 3D display and interaction mechanisms means that extending these diagrams to 3D is now feasible.
Rodgers, Peter +2 more
core
MetalsIn a previous article, an estimation procedure for calculating the liquidus and solidus lines of binary equilibrium phase diagrams was presented. In this article, keeping the thermodynamic basics, the estimation method for the approximate calculation of ...
Gergely Kőrösy +2 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source