Results 61 to 70 of about 251,123 (306)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The Phonon Entropy of Transition Metals and Alloys: Effects of Impurities and of a Martensitic Phase Transition [PDF]

, 2006
For a fixed configuration of ions on a given crystalline lattice, low energy excitations around the static average configuration can be thermally activated and will contribute to the entropy of the system.
Delaire, Olivier
core   +1 more source

Femtometer displacement resolution with phase-insensitive Doppler sensing

Optics Letters, 2019
The measurement of extremely small displacements is of utmost importance, both for fundamental studies [1-4], and practical applications [5-7]. One way to estimate a small displacement is to measure the Doppler shift generated in light reflected off an object moving with a known periodic frequency.
Bethany J. Little, Julián Martínez-Rincón, Umberto Bortolozzo, Stefania Residori, John C. Howell   +4 more
openaire   +3 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Phase object data obtained from defocused laser speckle displacement

, 2004
An optical technique that is based on defocused digital speckle photography is proposed for the evaluation of phase objects. Phase objects are different kinds of transparent or semi-transparent media that allow light to be transmitted.
Sjödahl, Mikael,, Benckert, Lars, Johansson, Eva-Lena   +2 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

MEASUREMENTS OF STRAIN FIELDS DUE TO NANOSCALE PRECIPITATES USING THE PHASE IMAGE METHOD

Image Analysis and Stereology, 2011
Owing the phase image method (Hytch, 1998), strain fields can be derived from HREM images. The method is here applied to the nanoscale precipitates responsible for hardening in Aluminum alloys.
Patricia Donnadieu, Kenji Matsuda, Thierry Epicier, Joel Douin   +3 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Quantitative Analysis Method of Conversion of Type of Microscopic Remaining Oil Based on CT Technology

Energies
The distribution and mutual conversion of remaining oil during the process of oilfield development constitute an important basis for guiding the exploitation of remaining oil potential.
Chun Feng, Linghui Sun, Zhengming Yang
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source