Results 51 to 60 of about 7,448,970 (353)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Predicting weld distortion in the design of automotive components [PDF]

open access: yes, 2007
This project was set up in order to investigate whether it may be valid to use a simplified approach to weld distortion prediction in order to make an assessment of the distortions occurring in a welded structure.
O'Brien, Roger William
core  

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Modeling and Analysis of High-Power Ti:sapphire Laser Amplifiers–A Review

open access: yesApplied Sciences, 2019
We have introduced several factors that can be useful for the modeling and analysis of high-power Ti:sapphire laser amplifiers. The amplification model includes the phase distortion effect caused by the atomic phase shift (APS) in gain medium and the ...
Jihoon Jeong   +4 more
doaj   +1 more source

Three-Phase Four-Wire Inverter for Grid Emulator Under Wide Inductance Variation to Evaluate the Performance of Distributed Generator

open access: yesIEEE Open Journal of Industry Applications, 2023
This article presents a three-phase four-wire inverter to generate voltage sources under wide filter inductance variation. The voltage sources with distortion and unbalance are to emulate grid voltages.
Tsai-Fu Wu   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Noise considerations when determining phase of large-signal microwave measurements

open access: yes, 2006
Advances in microwave instrumentation now make it feasible to accurately measure not only the magnitude spectrum, but also the phase spectrum of wide-bandwidth signals.
Scott, Jonathan B.   +3 more
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy