Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Fast Phase Estimation Approach for Distributed Scatterer Based on Power Method
IEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingDistributed scatterer (DS) possesses a medium signal-to-noise ratio, and its interferometric phase is typically estimated from sample covariance matrix (SCM) using phase linking algorithm. However, the phase estimation of DS is very time consuming.
Chuanguang Zhu +4 more
doaj +1 more source
Phase estimation of definite photon number states by using quantum circuits. [PDF]
Sci Rep, 2023 Najafi P, Naeimi G, Saeidian S.
europepmc +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Growth phase estimation for abundant bacterial populations sampled longitudinally from human stool metagenomes. [PDF]
Nat Commun, 2023 Lim JJ +5 more
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
An Adaptable Phase-Tracking System for Parkinsonian Rest Tremor: Design and In-Clinic Feasibility
IEEE Journal of Translational Engineering in Health and MedicineBackground: Tremor is the most common movement disorder and a prevalent symptom of neurodegenerative conditions such as Parkinson’s disease (PD).
Beatriz S. Arruda +7 more
doaj +1 more source
A Novel Method for Interferometric Phase Estimation in Dual-Channel Cancellation. [PDF]
Sensors (Basel), 2022 Huang L, Liu A, Huang Z, Xu H, Han D.
europepmc +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Noise analysis of Grover and phase estimation algorithms implemented as quantum singular value transformations for a small number of noisy qubits. [PDF]
Sci Rep, 2023 Ijaz MA, Faryad M.
europepmc +1 more source