Results 141 to 150 of about 1,835,350 (291)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Interferometric binary phase estimations

open access: yesQuantum
We propose an interferometric scheme where each photon returns one bit of the binary expansion of an unknown phase. It sets up a method for estimating the phase value at arbitrary uncertainty. This strategy is global, since it requires no prior information, and it achieves the Heisenberg bound independently of the output statistics.
Simone Roncallo, Xi Lu, Lorenzo Maccone
openaire   +3 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Progressive InSAR phase estimation

open access: yes, 2020
This paper introduces a novel scheme to progressively estimate interferometric phases from a stack of synthetic aperture radar (SAR) images. The scheme is shown to yield comparable performance to full-covariance algorithms for a realistic decorrelation scenario.
openaire   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Data-centric multi-task surgical phase estimation with sparse scene segmentation. [PDF]

open access: yesInt J Comput Assist Radiol Surg, 2022
Sanchez-Matilla R   +4 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A state space modeling approach to real-time phase estimation. [PDF]

open access: yesElife, 2021
Wodeyar A   +4 more
europepmc   +1 more source

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