Results 131 to 140 of about 4,563,981 (306)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Functional oxide films obtained from chemical solutions

Тонкие химические технологии, 2011
The article presents a brief review of research in the field of film material science of functional oxides (high-temperature superconductors, ferroelectrics, piezoelectrics and pyroelectric, abrasives) synthesized in the context of chemical engineering ...
Yu. Ya. Tomashpolsky
doaj  

Metastable Ordered Mesoporous h‐LuFeO3 Thin Films Prepared by Soft‐Templating: Optical, Electronic, and Magnetic Properties

Advanced Materials Interfaces
A sol–gel‐based soft‐templating strategy for the synthesis of a hexagonal rare‐earth orthoferrite and characterization of its structural, optical, electronic, and magnetic properties are reported.
Christian Suchomski, Christian Reitz, Vipin Kumar, Igor Djerdj, Marcus Einert, Torsten Brezesinski, Bernd Smarsly   +6 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Regarding Sigma Phase Formation [PDF]

JOM, 1953
David S. Bloom, Nicholas J. Grant
openaire   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Elucidating the effect of silicon on Fe-Zn phase formation in galvanized steel via advanced TEM [PDF]

BIO Web of Conferences
Minenkov Alexey, Knapp Johannes, Mörtlbauer Thomas, Groiss Heiko   +3 more
doaj   +1 more source

Phase Formation Process in CdSe Thin Films

East European Journal of Physics
In this work, thin films of cadmium selenide of difrent thicknesses were obtained by chemical deposition and the processes of phase formation in them were studied. Thin layers with a thickness of d = 150 – 500 nm were obtained.
L.N. Ibrahimova, N.M. Abdullayev, M.E. Aliyev, G.A. Garashova, Y.I. Aliyev   +4 more
doaj   +1 more source