Results 241 to 250 of about 4,565,563 (306)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Unconventional pathway for the gas-phase formation of 14π-PAHs <i>via</i> self-reaction of the resonantly stabilized radical fulvenallenyl (C₇H₅˙). [PDF]

Chem Sci
Li W, Wu M, Wang C, Huang J, Yang J, Xu M, Zhang F, Yang T, Zhao L.   +8 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Nanoscale liquid Al phase formation through beam heating of MgAl₂O₄ in TEM. [PDF]

Nanoscale Adv
Lee SB, Chae JY, Han HN.
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Pulse electrodeposition of CuSbS₂ thin films: Role of Cu/Sb precursor ratio on the phase formation and its performance as photocathode for hydrogen evolution^§. [PDF]

Heliyon
Avilez García RG, Cerdán-Pasarán A, Enríquez JP, Mathews NR.   +3 more
europepmc   +1 more source

Phase separation and pattern formation

, 1985
Langer, J.S., Beenakker, C.W.J.
openaire   +1 more source

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Galvanostatic phase formation

Journal of Solid State Electrochemistry, 2014
The results of a theoretical study on initial stages of electrodeposition under galvanostatic conditions are presented. The model of three-dimensional nucleation and growth under these conditions is developed. This model is used to calculate the times dependences of the overpotential, number of clusters formed on the electrode, and nucleation rate. The
Vladimir A. Isaev, Olga V. Grishenkova
openaire   +1 more source

Developmental Pattern Formation in Phases

Trends in Cell Biology, 2015
Cells in developing organs undergo a series of changes in their transcriptional state until a complete repertoire of cell types is specified. These changes in cell identity, together with the control of tissue growth, determine the pattern of gene expression in the tissue.
Anna, Kicheva, James, Briscoe
openaire   +2 more sources