Results 41 to 50 of about 685,124 (213)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Active Landslide Mapping Along the Karakoram Highway Alternate Route in North Pakistan; Implications for the Expansion of China−Pakistan Economic Corridor

Remote Sensing
Slowly moving active landslides threaten infrastructure, particularly along highway routes traversing active mountainous ranges. Detecting and characterizing such landslides in highly elevated mountainous terrains is challenging due to their ...
Said Mukhtar Ahmad, Teng Wang, Mumtaz Muhammad Shah, Saad Khan   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Risk assessment of building and infrastructure using InSAR-derived deformation gradients and pattern variations in the Beijing plain, China

International Journal of Digital Earth
Ground surface deformation and spatial differential deformation pose significant risks to urban buildings and infrastructures. Previous studies analyzed deformation risks using Interferometric Synthetic Aperture Radar (InSAR) but often lacked integration
Shicheng Zuo, Mingsheng Liao, Jie Dong, Ru Wang, Shaokun Guo, Feikai Lin, Nan Wang, Dongxiao Zhang   +7 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Planar Phase Gradient Metasurface Antenna With Low RCS

IEEE Access, 2018
A low radar cross section (RCS) planar antenna using phase gradient metasurface is proposed in this paper. The proposed antenna works in the X-band and is fed by a parallel plate waveguide power divider.
Bo Li, Xiaobo Liu, Hongyu Shi, Chun Yang, Qi Chen, Anxue Zhang   +5 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Strain Modeling and Revealed Slope Motion Mechanisms of the Taoping Paleo-Landslide from InSAR Observations

Remote Sensing
The Taoping paleo-landslide poses a significant risk to local residents and critical infrastructure. However, traditional field surveys and deformation monitoring methods are often inadequate for capturing subtle, localized deformation characteristics ...
Siyu Lai, Yinghui Yang, Qian Xu, Qiang Xu, Jyr-Ching Hu, Shi-Jie Chen   +5 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source