Results 131 to 140 of about 1,964,480 (312)
Hawaii Deep Water Program Phase II-B task 1 : environmental review plan
, 1986 This Environmental Review Plan discusses the proposed commercial cable program and its alternatives and options. It compiles and updates pertinent information; identifies the related environmental issues and required permits; and outlines the contents of
Parsons Hawaii
core
Phase II of the genomic effort [PDF]
Journal of Synchrotron Radiation, 2000 S S, Hasnain, H, Kamitsubo, D M, Mills
openaire +2 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Hawaii Deep Water Cable Program federally funded - phase II : test cable selection [PDF]
, 1985 The cable selection task is another step towards accomplishing the goals and objectives of the Hawaii Deep Water Cable (HDWC) Program. The primary purpose of this task is the selection of a cable that best meets the Program's system and subsystem ...
The Ralph M. Parsons Company DBA Parsons Hawaii
core
Pulmonary tuberculosis case detection in South Sudan
South Sudan Medical Journal, 2012 Background: The National Tuberculosis (TB) Control Programme in South Sudan was created in 2006, and non-governmental organizations (NGOs) are its main implementers. Pulmonary tuberculosis (PTB) is a major public health threat.
David L. Lukudu
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Real-Time Traffic Prediction for Advanced Traffic Management Systems: Phase II
, 2006 This project focuses on systems of signalized intersections, with the goals of: 1) conducting a detailed empirical evaluation of the traffic flow model used to predict evolution of traffic conditions, and 2) posing and solving an optimization problem ...
Davis, Gary A. +2 more
core
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source