Results 81 to 90 of about 1,964,480 (312)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Peace Wall (Phase II) Image 016

, 2019
The Peace Wall Phase II organized a “Find Your Own Peace” Workshop and collaborated with PSU Model UN on April 13-14, combining its workshop with the Eleventh Annual Plymouth Model UN High School Conference. Here, Museum Director Cynthia Robinson working

core  

Prospective, open, multi-centre phase I/II trial to assess safety and efficacy of neoadjuvant radiochemotherapy with docetaxel and oxaliplatin in patients with adenocarcinoma of the oesophagogastric junction [PDF]

, 2013
Background: This phase I/II-trial assessed the dose-limiting toxicities (DLT) and maximum tolerated dose (MTD) of neoadjuvant radiochemotherapy (RCT) with docetaxel and oxaliplatin in patients with locally advanced adenocarcinoma of the oesophagogastric ...
Klautke, Gunther, Galle, Peter R., Brenner, Baruch, Arnold, Dirk, Roessler, Hans-Peter, Thomaidis, Thomas, Schimanski, Carl Christoph, Schmidberger, Heinz, Rödel, Claus, Gockel, Ines, Möhler, Markus, Trarbach, Tanja, Lang, Hauke   +12 more
core   +1 more source

Synthesis and characterization of ethanolic extract of nutgalls of the plant Quercus infectoria silver nitrate nanoparticles incorporated chitosan based scaffold, and their in-silico study for wound healing activity

Results in Surfaces and Interfaces
Quercus infectoria is a popular medicinal plant used in many parts of the world as a treatment for various health conditions. The main components found in the galls of Quercus infectoria are tannin (50–70%) and small amounts of free Gallic acid and ...
Madhusmita Sahu, Kamakshi, Jyotirmaya Sahoo, Sudhansu Ranjan Swain, Sakshi Gupta, Nishat Fatma, Geetanjali Mehara   +6 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Peace Wall (Phase II) Image 021

, 2019
The Peace Wall Phase II organized a “Find Your Own Peace” Workshop and collaborated with PSU Model UN on April 13-14, combining its workshop with the Eleventh Annual Plymouth Model UN High School Conference. Students created two peace tiles, one to leave

core  

Hardening of an Al-Cu-Mg alloy containing type I and II S phase precipitates

, 2010
The effect of different thermo-mechanical treatments on the hardness of the 2024 (Al-Cu-Mg) alloy was studied. Artificial ageing was conducted through heating at a constant rate to specific temperatures followed by rapid cooling.
Starink, M.J., Wang, S.C., Parel, T.S.
core   +1 more source

Difference frequency generation by quasi-phase matching in periodically intermixed semiconductor superlattice waveguides [PDF]

, 2011
Wavelength conversion by difference frequency generation is demonstrated in domain-disordered quasi-phase-matched waveguides. The waveguide structure consisted of a GaAs/AlGaAs superlattice core that was periodically intermixed by ion implantation.
David C. Hutchings, Helmy, A.S., Sean J. Wagner, Iliya Sigal, Wagner, S.J., Younis, U., Sigal, I., Holmes, B.M., Amr S. Helmy, Hutchings, D.C., Barry M. Holmes, Usman Younis, Aitchison, S.J., J. Stewart Aitchison   +13 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source