Results 1 to 10 of about 986,649 (268)

Phase Retardation Analysis in a Rotated Plane-Parallel Plate for Phase-Shifting Digital Holography

open access: yesJournal of Imaging, 2022
In this paper, we detail a phase-shift implementation in a rotated plane-parallel plate (PPP). Considering the phase-shifting digital holography application, we provide a more precise phase-shift estimation based on PPP thickness, rotation, and mutual ...
Igor Shevkunov, Nikolay V. Petrov
doaj   +1 more source

Pembrolizumab combined with low-dose cyclophosphamide and intra-tumoral injection of the toll-like receptor 4 agonist G100 in patients with advanced pretreated soft tissue sarcoma: results from the PEMBROSARC basket study

open access: yesJournal of Hematology & Oncology, 2022
Soft tissue sarcomas (STS) are heterogeneous mesenchymal tumors with limited therapeutic options in the advanced setting. Immune checkpoint inhibitors have been shown to have significant clinical activity in inflamed STS which are characterized by the ...
Mariella Spalato-Ceruso   +12 more
doaj   +1 more source

Ultrafast and Multiplexed Bacteriophage Susceptibility Testing by Surface Plasmon Resonance and Phase Imaging of Immobilized Phage Microarrays

open access: yesChemosensors, 2022
In the context of bacteriophage (phage) therapy, there is an urgent need for a method permitting multiplexed, parallel phage susceptibility testing (PST) prior to the formulation of personalized phage cocktails for administration to patients suffering ...
Larry O'Connell   +5 more
doaj   +1 more source

Enhancing Phase Measurement by a Factor of Two in the Stokes Correlation

open access: yesEngineering Proceedings, 2023
Phase loss is a typical problem in the optical domain, and optical detectors only measure the amplitude distribution of a signal without its phase. However, an optimal phase is desired in a variety of practical applications, such as optical metrology ...
Amit Yadav   +3 more
doaj   +1 more source

Salinomycin Treatment Specifically Inhibits Cell Proliferation of Cancer Stem Cells Revealed by Longitudinal Single Cell Tracking in Combination with Fluorescence Microscopy

open access: yesApplied Sciences, 2020
A cell line derived from a tumor is a heterogeneous mixture of phenotypically different cells. Such cancer cell lines are used extensively in the search for new anticancer drugs and for investigating their mechanisms of action.
Sofia Kamlund   +3 more
doaj   +1 more source

Single Shot Lensless Interferenceless Phase Imaging of Biochemical Samples Using Synchrotron near Infrared Beam

open access: yesBiosensors, 2022
Phase imaging of biochemical samples has been demonstrated for the first time at the Infrared Microspectroscopy (IRM) beamline of the Australian Synchrotron using the usually discarded near-IR (NIR) region of the synchrotron-IR beam.
Molong Han   +10 more
doaj   +1 more source

Low-Photon Counts Coherent Modulation Imaging via Generalized Alternating Projection Algorithm

open access: yesApplied Sciences, 2022
Phase contrast imaging is advantageous for mitigating radiation damage to samples, such as biological specimens. For imaging at nanometer or atomic resolution, the required flux on samples increases dramatically and can easily exceed the sample damage ...
Meng Sun   +4 more
doaj   +1 more source

Quantifying the Rate, Degree, and Heterogeneity of Morphological Change during an Epithelial to Mesenchymal Transition Using Digital Holographic Cytometry

open access: yesApplied Sciences, 2020
Cells in complex organisms can transition between epithelial and mesenchymal phenotypes during both normal and malignant physiological events. These two phenotypes are not binary, but rather describe a spectrum of cell states along an axis.
Sofia Kamlund   +4 more
doaj   +1 more source

Evaluation of the Impact of Imprinted Polymer Particles on Morphology and Motility of Breast Cancer Cells by Using Digital Holographic Cytometry

open access: yesApplied Sciences, 2020
Breast cancer is the second most common cancer type worldwide and breast cancer metastasis accounts for the majority of breast cancer-related deaths. Tumour cells produce increased levels of sialic acid (SA) that terminates the monosaccharide on glycan ...
Megha Patel   +4 more
doaj   +1 more source

Phase 2 trial of intravenous oncolytic virus JX-594 combined with low-dose cyclophosphamide in patients with advanced breast cancer

open access: yesExperimental Hematology & Oncology, 2022
Breast cancer is one the most common cause of cancer death in women worldwide. We report here the first phase II study investigating a virus genetically engineered for tumor-selective replication in patients with breast cancer.
Sophie Cousin   +7 more
doaj   +1 more source

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