Results 141 to 150 of about 986,649 (268)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Resolution-enhanced transport of intensity phase imaging using contrast transfer function reformulation and SNR-guided deconvolution. [PDF]

Biomed Opt Express
Shanmugavel SC, Zhu Y.
europepmc   +1 more source

Quantum enhanced non-interferometric quantitative phase imaging. [PDF]

Light Sci Appl, 2023
Ortolano G, Paniate A, Boucher P, Napoli C, Soman S, Pereira SF, Ruo-Berchera I, Genovese M.   +7 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Quantitative phase imaging with temporal kinetics predicts hematopoietic stem cell diversity. [PDF]

Nat Commun
Yogo T, Iwamoto Y, Becker HJ, Kimura T, Ishida R, Sugiyama-Finnis A, Yokomizo T, Suda T, Ota S, Yamazaki S.   +9 more
europepmc   +1 more source

Free-electron Ramsey-type interferometry for enhanced amplitude and phase imaging of nearfields. [PDF]

Sci Adv, 2023
Bucher T, Ruimy R, Tsesses S, Dahan R, Bartal G, Vanacore GM, Kaminer I.   +6 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Quantitative phase imaging endoscopy with a metalens. [PDF]

Light Sci Appl
Shanker A, Fröch JE, Mukherjee S, Zhelyeznyakov M, Brunton SL, Seibel EJ, Majumdar A.   +6 more
europepmc   +1 more source

Asymmetric metasurface photodetectors for single-shot quantitative phase imaging. [PDF]

Nanophotonics, 2023
Liu J, Wang H, Li Y, Tian L, Paiella R.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source