Results 51 to 60 of about 220,278 (302)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Research on the three-phase load imbalance control of the active distribution network based on the distributed power flow controller

open access: yesFrontiers in Energy Research
In the background of the global commitment to low-carbon renewable energy transformation, new energy sources such as distributed wind–solar storage and charging and single-phase loads, such as electric vehicles, are connected to the distribution network.
Guowei Guo   +9 more
doaj   +1 more source

Gain/phase imbalance cancellationtechnique in LINC transmitters

open access: yesElectronics Letters, 1998
A new technique for correcting the gain/phase imbalance in LINC transmitters is presented. The technique employs a feedback signal to generate an error signal, consisting mainly of intermodulation distortion. A direct search method is used to optimise the gain/phase imbalance for correction.
S. Ampem-Darko, H.S. Al-Raweshidy
openaire   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Differentiated Governance Strategies for Distribution Transformer Overload and Three-Phase Imbalance Considering Source-Load Regulation

open access: yesZhongguo dianli
Aiming at the mixed problems of three-phase imbalance and heavy overload of distribution transformers caused by large-scale access of single-phase distributed photovoltaic and single-phase charging piles, a differentiated governance strategy for heavy ...
Qiang YANG   +7 more
doaj   +1 more source

Dynamic reconfiguration of three‐phase imbalanced distribution networks considering soft open points

open access: yesEnergy Conversion and Economics, 2023
The characteristics of three‐phase imbalances are present in medium‐ and low‐voltage distribution networks. Integrating single‐phase distributed generation (DG) exacerbates network imbalances, resulting in increased power losses and potential safety ...
Xingquan Ji   +5 more
doaj   +1 more source

Mechanism analysis of unbalanced three-phase inrush current of Y0D transformer

open access: yesEnergy Reports, 2022
During the energization of transformer with high-impedance (HT), the zero-sequence overcurrent protection (ZSOCP) often malfunction with the inrush current of primary winding (iP-inrush) shows a large unbalance.
Wenbin Cao   +5 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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