Results 171 to 180 of about 4,408,406 (294)

A Dual‐Membrane Biomimetic Nanoplatform Enables Triple‐Modal Therapy Against SARS‐CoV‐2 Through Viral Decoy, Inflammation Neutralizing, and Intracellular RNAi

Advanced Science, EarlyView.
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li, Bohan Zhang, Chao Shang, Yi Li, Te Zhao, Shengya Liu, Dan Liu, Junwei Che, Cuiling Zhang, Pinghui Wu, Wenjie Yang, Junjie Ding, Yuhua Ran, Yanan Zhai, Haihua Xiao, Jing Gao, Xiao Li, Chunsheng Gao, Lin Li, Zhiping Li   +19 more
wiley   +1 more source

A Novel MSPLL-Based Method for Frequency Synthesis in Hydrogen MASER. [PDF]

Sensors (Basel)
Simariya D, Johnson SR, Dharmappa D, Dakkumalla S, Dubey PR, Vasanthakumar RM, Daniel DA, Thirukkodi SG.   +7 more
europepmc   +1 more source

Mechanically Robust, Self‐Healable, and Cryotolerant GelMA Hydrogel for Wearable Tactile Sensors with Enhanced Durability, Lifetime, and Environmental Stability

Advanced Science, EarlyView.
A mechanically robust, self‐healable, moisturizing, cryotolerant and adhesive GelMA hydrogel is developed by incorporating polyvinyl alcohol, acrylic acid, sodium tetraborate, and glycerol into GelMA matrix via a photoinitiated polymerization process. The hydrogel‐derived omni‐healable ionotronic pressure sensor can sensitively and consistently monitor
Zhikang Li, Gengyu Han, Boqing Jia, Jijian Lu, Changxu Zhang, Bin Wang, Jiaxiang Wang, Kang Zhao, Muhammad Afzal Khan Qureshi, Lan Yu, Min Li, Guoxi Luo, Tong Wang, Qijing Lin, Weishi Li, Libo Zhao, Yumeng Xue   +16 more
wiley   +1 more source

10^-21-Level optical frequency dissemination over 2067 km of noise-loaded field-deployed fiber network. [PDF]

Light Sci Appl
Chen FX, Li LB, Chen JP, Zhao K, Guan JY, Xu Y, Hou L, Zhou F, Peng CZ, Zhang Q, Jiang HF, Pan JW.   +11 more
europepmc   +1 more source

Distinct Cleavage Trajectories Mediated by DNA and RNA Substrate in Argonaute From Methanocaldococcus Fervens

Advanced Science, EarlyView.
This study characterizes MfAgo, an enzyme exhibiting highly efficient DNA‐guided DNA and RNA cleavage capability. Precise RNA cleavage strictly requires dimerization to stabilize the PIWI‐loop region, while its robust DNA cleavage functions in a dimerization‐independent manner.
Fuyong Huang, Taiyu Chen, Meng Fang, Qinmiao Duanmu, Kangle Mu, Yuqi Bi, Siwei Xu, Xin Tao, Jiening Wang, Shan Wu   +9 more
wiley   +1 more source

CRISPRi targeting to the <i>Neisseria gonorrhoeae</i> R-loop or G4 mutant region restores pilin antigenic variation. [PDF]

mBio
Metaane S, Seifert HS.
europepmc   +1 more source

Passive Metasurface Tweezers for Multi‐Scale Orbital Transport and Trapping on Elastic Plates

Advanced Science, EarlyView.
Passive labyrinthine phase encoding converts single‐channel excitation into localized flexural‐wave vortices with programmable orbital angular momentum. The resulting vortex fields enable cross‐scale particle manipulation, including orbital transport, central confinement, and rotational actuation.
Zeyang Bi, Zhiqiang Li, Yunkang Ren, Yugui Peng, Xuefeng Zhu, Liuxian Zhao, Jun Yang, Chuanxing Bi   +7 more
wiley   +1 more source

A Subsampling Phase-Locked Loop with a Dual Charge Pump Based on Capacitor Multipliers for CMOS Image Sensor. [PDF]

Micromachines (Basel)
Lin Y, Wang B, Jin L, Tang Z, Ye F, Xie R, Wu L, Shi G, Liu H.   +8 more
europepmc   +1 more source

Supramolecular Zinc–Polyphenol Coordination Assemblies Mitigate Colonic Inflammation by Regulating Mucosal Barrier and Microbiome

Advanced Science, EarlyView.
A carrier‐free zinc‐coordinated polyphenol nanoplatform (ZnCA NPs) is designed as an “all‐in‐one” therapeutic strategy for intestinal inflammation. The ZnCA NPs exhibit enhanced colonic accumulation and broad‐spectrum reactive oxygen and nitrogen species scavenging.
Qiwen Xie, Mai Ye, Xuexia Liu, Jing Wang, Ying Chen, Lu Tan, Jinheng Fu, Xiaochang Huang   +7 more
wiley   +1 more source

Bulk ferroelectric heterostructures. [PDF]

Sci Adv
Li Y, Yang Z, Chen Y, Zhang Z, Tang YL, Smith M, Lindley M, Cao X, Kleppe AK, Koemets E, Hopkinson DG, Bell AJ, Milne SJ, Feteira A, Haigh SJ, Eggeman AS, Pan J, Shi J, Yang Y, Hall DA.   +19 more
europepmc   +1 more source