Results 51 to 60 of about 560,798 (337)
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
High Performance Lyot and PIAA Coronagraphy for Arbitrarily shaped Telescope Apertures
Two high performance coronagraphic approaches compatible with segmented and obstructed telescope pupils are described. Both concepts use entrance pupil amplitude apodization and a combined phase and amplitude focal plane mask to achieve full ...
Belikov, Ruslan +4 more
core +2 more sources
Inverse design for phase mask lithography
We have developed a method for designing the diffractive optics used in phase mask lithography. Genetic algorithms were used to inverse-design a grating's relief profile and associated exposure conditions so that desired periodic structures are formed. An experimentally promising grating designed to produce helices is demonstrated.
James W, Rinne +2 more
openaire +2 more sources
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Post-coronagraphic tip-tilt sensing for vortex phase masks: the QACITS technique [PDF]
Small inner working angle coronagraphs, like the vortex phase mask, are essential to exploit the full potential of ground-based telescopes in the context of exoplanet detection and characterization.
Absil, Olivier +3 more
core +4 more sources
Holographically encoded volume phase masks [PDF]
We present here a method to create spectrally addressable phase masks by encoding phase profiles into volume Bragg gratings, allowing these holographic elements to be used as phase masks at any wavelength capable of satisfying the Bragg condition of the hologram. Moreover, this approach enables the capability to encode and multiplex several phase masks
Segall, Marc +4 more
openaire +2 more sources
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Theory and laboratory tests of the multi-stage phase mask coronagraph
A large number of coronagraphs have been proposed to overcome the ratio that exists between the star and its planet. The planet finder of the Extremely Large Telescope, which is called EPICS, will certainly need a more efficient coronagraph than the ones
Baudoz, P. +3 more
core +2 more sources
Placement sensitivity to aberration in optical imaging [PDF]
Theories are developed to quantify the shift of image intensity extremum (/spl Delta/x) due to aberration. The theory on real, one-dimensional mask spectrum has been extended to complex, two-dimensional mask spectrum under coherent and partially coherent
Lam, EYM, Mak, GYH, Wong, AKK
core +1 more source

