Results 71 to 80 of about 5,106,399 (296)

A Comparative Study of Adaptive Interlimb Coordination Mechanisms for Self-Organized Robot Locomotion

open access: yesFrontiers in Robotics and AI, 2021
Walking animals demonstrate impressive self-organized locomotion and adaptation to body property changes by skillfully manipulating their complicated and redundant musculoskeletal systems.
Tao Sun   +6 more
doaj   +1 more source

Compensation of nonlinear self-phase modulation with phase modulators

open access: yesElectronics Letters, 2002
The compensation of the nonlinear self-phase modulation of a 10 Gbit/s RZ data stream with phase modulators has been experimentally demonstrated. The electrical waveform that drives the phase modulators is synthesised from the recovered 10 GHz clock and its 20 GHz harmonic.
C. Xu, L. Mollenauer, Xiang Liu
openaire   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Wideband Burst-by-Burst Adaptive Modulation Using Reduced-Complexity In-Phase/Quadrature-Phase Turbo Equalization

open access: yes, 2002
The performance of burst-by-burst adaptive modulation is studied in conjunction with reduced complexity turbo equalization over a wideband multi-path Rayleigh fading channel.
Wong, C H, Yeap, B L, Hanzo, L
core   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Large Phase-by-Phase Modulations in Atomic Interfaces [PDF]

open access: yesPhysical Review Letters, 2015
Phase-resonant closed-loop optical transitions can be engineered to achieve broadly tunable light phase shifts. Such a novel phase-by-phase control mechanism does not require a cavity and is illustrated here for an atomic interface where a classical light pulse undergoes radian level phase modulations all-optically controllable over a few micron scale.
Artoni M, Zavatta A
openaire   +3 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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