Results 41 to 50 of about 378,338 (267)
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The effect of AM noise on correlation phase-noise measurements [PDF]
IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, 2007 We analyze the phase-noise measurement methods in which correlation and averaging is used to reject the background noise of the instrument. All the known methods make use of a mixer, used either as a saturated phase detector or as a linear synchronous detector. Unfortunately, AM noise is taken in through the power-to-dc-offset conversion mechanism that
Rubiola, Enrico, Boudot, Rodolphe
openaire +4 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Design Techniques for High-Speed Wireline Transmitters
IEEE Open Journal of the Solid-State Circuits Society, 2021 Wireline transmitters operating at tens of gigabits per second pose challenging design issues ranging from limited bandwidths to severe sensitivity to jitter.
Behzad Razavi
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Self-Oscillation Multicarrier Light Source Based on Recirculating Frequency Shift Loop
IEEE Photonics Journal, 2021 A novel scheme of self-oscillation multicarrier light source based on recirculating frequency shift loop (RFSL) is proposed and experimentally demonstrated in this paper.
Long Zhang +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Extended Noise Analysis Model of CW-type Radar Sensors with IQ Down-Conversion [PDF]
Radioengineering, 2018 CW-type structures belong to the most frequently employed radars, especially in a form of small sensors used, for example, in security applications or automotive industry.
V. Jenik, P. Hudec, P. Panek
doaj
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source