Results 61 to 70 of about 1,684,562 (352)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Design Techniques for High-Speed Wireline Transmitters

open access: yesIEEE Open Journal of the Solid-State Circuits Society, 2021
Wireline transmitters operating at tens of gigabits per second pose challenging design issues ranging from limited bandwidths to severe sensitivity to jitter.
Behzad Razavi
doaj   +1 more source

Characterization of Power-to-Phase Conversion in High-Speed P-I-N Photodiodes

open access: yes, 2011
Fluctuations of the optical power incident on a photodiode can be converted into phase fluctuations of the resulting electronic signal due to nonlinear saturation in the semiconductor.
Datta, S.   +6 more
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Self-Oscillation Multicarrier Light Source Based on Recirculating Frequency Shift Loop

open access: yesIEEE Photonics Journal, 2021
A novel scheme of self-oscillation multicarrier light source based on recirculating frequency shift loop (RFSL) is proposed and experimentally demonstrated in this paper.
Long Zhang   +6 more
doaj   +1 more source

Constellation Optimization in the Presence of Strong Phase Noise

open access: yes, 2013
In this paper, we address the problem of optimizing signal constellations for strong phase noise. The problem is investigated by considering three optimization formulations, which provide an analytical framework for constellation design.
Amat, Alexandre Graell i   +3 more
core   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

Extended Noise Analysis Model of CW-type Radar Sensors with IQ Down-Conversion [PDF]

open access: yesRadioengineering, 2018
CW-type structures belong to the most frequently employed radars, especially in a form of small sensors used, for example, in security applications or automotive industry.
V. Jenik, P. Hudec, P. Panek
doaj  

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

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