Results 91 to 100 of about 11,948,985 (352)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Remote SensingPhase optimization, aimed to enhance phase signal-to-noise ratio, is a critical component of the distributed scatterer interferometric synthetic aperture radar technique and directly determines the fineness and reliability of deformation monitoring. As a
Shijin Li +8 more
doaj +1 more source
Sensors, 2019 Phase correlation is one of the widely used image registration method in medical image processing and remote sensing. One of the main limitations of the phase correlation-based registration method is that it can only cope with Euclidean transformations ...
Xue Wan, Chenhui Wang, Shengyang Li
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design optimization of permanent magnet actuators. [PDF]
, 1992 This study describes the design optimization of permanent actuators, of both rotary and linear topologies. Parameter scanning, constrained single and multi-criterion optimization techniques are developed, with due emphasis on the efficient ...
Widdowson, G P
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Implementation Research and Practice, 2022 Background The public health impact of behavioral and biobehavioral interventions to prevent and treat mental health and substance use problems hinges on developing methods to strategically maximize their effectiveness, affordability, scalability, and ...
Karey L. O’Hara +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
IEEE Access, 2020 In this work, the Coyote Optimization Algorithm (COA) is implemented for estimating the parameters of single and three-phase power transformers. The estimation process is employed on the basis of the manufacturer's operation reports.
Mohamed I. Abdelwanis +4 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source