Results 81 to 90 of about 26,377 (290)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Low distortion automatic phase control circuit [PDF]

, 1974
A voltage controlled phase shifter is rendered substantially harmonic distortion free over a large dynamic input range by employing two oppositely poled, equally biased varactor diodes as the voltage controlled elements which adjust the phase shift ...
Hauge, G., Pederson, C. W.
core   +1 more source

Spectral Efficiency Optimization For Millimeter Wave Multi-User MIMO Systems

, 2018
As a key enabling technology for 5G wireless, millimeter wave (mmWave) communication motivates the utilization of large-scale antenna arrays for achieving highly directional beamforming. However, the high cost and power consumption of RF chains stands in
Hong, Mingyi, Shi, Qingjiang
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

A Center-Fed Beam-Steerable Series Antenna Array With a Wide Matching Bandwidth

IEEE Open Journal of Antennas and Propagation
In this paper, a center-fed beam-steerable series antenna array is presented that has both a wide matching bandwidth and easy control. The proposed matched feeding network for the series array is composed of impedance transformers and voltage-controlled ...
Sungeun Kim, Haegwon Park, Byung-Wook Min   +2 more
doaj   +1 more source

Ka-band MMIC beam steered transmitter array [PDF]

A 32-GHz six-element linear transmitter array utilizing monolithic microwave integrated circuit (MMIC) phase shifters and power amplifiers was designed and tested as part of the development of a spacecraft array feed for NASA deep-space communications ...
Duffy, L., Huang, J., Lubecke, V., Rascoe, D. L., Riley, A. L.   +4 more
core   +1 more source

Fabrication and measurements of hybrid Nb/Al Josephson junctions and flux qubits with pi-shifters

, 2014
We describe fabrication and testing of composite flux qubits combining Nb- and Al-based superconducting circuit technology. This hybrid approach to making qubits allows for employing pi-phase shifters fabricated using well-established Nb-based technology
Beckmann, D., Bolginov, V. V., Egorov, S. V., Fedorov, K. G., Oboznov, V. A, Ryazanov, V. V., Shcherbakova, A. V., Shkolnikov, V. O., Shulga, K. V., Ustinov, A. V., Wolf, M. J.   +10 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Design and Optimization of Highly Miniaturized Liquid Crystal Phase Shifters Based on Defected Ground Structures

IEEE Journal of Microwaves
This paper presents a fast and compact design method for planar liquid crystal (LC) phase shifters, using circuit models based on filter design principles.
Robin Neuder, Marc Spath, Martin Schubler, Alejandro Jimenez-Saez   +3 more
doaj   +1 more source